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Radiation induced lung injury (RILI) is a common complication after radiation therapy of breast tumors and bone marrow transplantation pretreatment, and it is a critical limiting factor of radiotherapy doses in patients. Once RILI progresses to the radiation-induced pulmonary fibrosis stage, it seriously reduces the patient’s quality of life, while causing the patient’s respiratory failure and eventually leading to death. Ionizing radiation (IR) can induce cell injuries, including apoptosis, epithelial-mesenchymal transition, senescence, pyroptosis and ferroptosis, and these injuries can play an important role in the occurrence and development of radioactive lung injury. Starting from discussion of the occurrence of different forms of injury in different cells after IR stimulation, this review summarizes the pathogenesis of RILI and its clinical prevention and treatment.
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Objective To explore the feasibility of one-stop examination with Revolution CT for axial perfusion of normal pancreas.Methods Thirteen patients who received axial perfusion scan by one-stop examination with Revolution CT were analyzed as perfusion group.Two radiologists measured pancreatic CT perfusion (CTP) parameters independently and selected optimal phase for CTA and three phases of enhanced images.The effect dose (ED) was calculated.Eighteen patients who underwent abdominal enhanced CT and CTA with spiral scan were included as control group.Patients in both groups had no pancreatic disorders.The interobserver variation of CTP parameters was estimated.Two independent radiologists separated the superior pancreaticoduodenal artery (SPDA) image into 5 points according to image quality,and the consistency was assessed.The subjective points of SPDA image quality of two groups was compared.CT value,images noise,CNR and SNR of SPDA on CTA images and those of pancreas on three phases enhanced scan images between two groups were compared.Results ICC values of all CTP parameters were higher than 0.75.The ED of perfusion protocol was (24.52±-0.01)mSv.The subjective image scores of SPDA on CTA images in both groups were both 5,the consistency was good (Kappa=0.629,0.769).The CT value,CNR,and SNR of SPDA on CTA images of CTP group were higher than those of control group (all P＜0.05).The CT value,CNR,and SNR of pancreas of CTP group were higher than those of control group in venous phase and balanced phase (all P＜0.05).Conclusion The pancreatic CT one-stop examination can be performed by Revolution CT scanner with maximum detector width with acceptable radiation dose,from which pancreatic CT perfusion data,enhanced images with high quality and better CTA images can be extracted.
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Objective To understand the status of stroke patients' perceived control and healthrelated quality of life,and to analyze the effect of perceived control on stroke patients' depression and health-related quality of life.Methods By convenience sampling,264 stroke patients were chosen to complete the questionnaire survey,Perceived Control Questionnaire,Hamilton Depression Scale and ShortForm Health Survey Scale-2.Results The score of patient's perceived control and health-related quality of life were (18.21±2.74),(46.62±11.56) points respectively.The perceived control had a negative correlation with the depression (r=-0.32,P ＜ 0.05),had a weak positive correlation with the body health (r=0.05,P ＜0.05),and had a positive correlation with the mental health of health-related quality of life (r=0.29,P ＜0.05),depression was negatively correlated with health-related quality of life of the body health,mental health (r=-0.26,-0.28,P ＜ 0.05).Conclusions Medical personal should improve the level of stroke patients' perceived control through various methods,to reduce depression and improve health related quality of life.
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Objective To understand the status of colleague support and colleague solidarity of nurses,and explore the relationship between colleague support and colleague solidarity.Methods A total of 231 nurses from Zhengzhou City were chosen using convenience sampling method to complete the questionnaire survey about colleague support and colleague sohdarity.Results The nurses' colleague support scored (76.34±2.75) totally and colleague solidarity scored (64.63±4.25) totally.In dimensions of nurses' perception of colleague support,head nurse support,support result,cooperation,sympathy establishment,awareness increasing were positively correlated with emotional unity dimension of colleague solidarity (r=0.32,0.26,0.27,0.30,0.28,all P＜ 0.05);head nurse support,support result,cooperation,awareness increasing,goal setting,action projects were positively correlated with academic unity dimension of colleague solidarity (r=0.30,0.28,0.25,0.29,0.27,0.26,all P ＜ 0.05);head nurse support,support result,cooperation,awareness increasing,action projects and process management were negatively correlated with negative views of colleague solidarity (r=-0.31,-0.27,-0.30,-0.23,-0.24,-0.27,all P ＜ 0.05).Conclusions Improving the nurse colleague-peer support can improve degree of colleague solidarity.
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It is urgent to construct the integrity of medical students on campus.Students of the first and fifth grade which are also the two special stages are investigated in the survey,According to the comparison of the honor credibility knowledge and behavior,the article summarized the effectiveness of contemporary medical education,and discussed the dialectical relationship between the integrity education of the medical students and medical integrity,to give full play to the clinical practice teaching as a significant role of the integrity education of medical students.