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Pakistan Journal of Pharmaceutical Sciences. 2018; 31 (5 Supp.): 2287-2290
in English | IMEMR | ID: emr-199864

ABSTRACT

To observe and analyze the therapeutic effect of systemic administration of methotrexate on caesarean section scar pregnancy. The 160 patients who had been confirmed with caesarean section scar pregnancy in our hospital were


selected research objects. They were randomly divided into two groups [research group and control group], each containing 80 patients. The research group was subjected to systemic administration of methotrexate, while control


group was applied with local administration of methotrexate. The total treatment effective rates of two groups were observed and compared. The total treatment effective rate of research group was higher than that of control group,


p<0.05; in terms of time required for â-HCG restoring to normal state, the research group was significantly shorter than control group, p<0.05; the time required for disappearing of scar lump for research group was shorter than that of


control group, p<0.05. No complications were observed for both groups. Systemic administration of methotrexate can significantly improve the curative effect for patients with caesarean section scar pregnancy

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