Neuro-Anatomical Evaluation of Human Suitability for Rural and Urban Environment by Using fMRI / 의학물리

The purpose of this study was to identify different cerebral areas of the human brain associated with rural and urban picture stimulation using a 3.0 Tesla functional magnetic resonance imaging (fMRI) and further to investigate the human suitability for rural and urban environments. A total of 27 right-handed participants (mean age: 27.3+/-3.7) underwent fMRI study on a 3.0T MR scanner. The brain activation patterns were induced by visual stimulation with each rural and urban sceneries. The participants were divided into two groups as 26 subjects favorable to rural scenery and 14 subjects unfavorable to urban scenery based on their filled-in questionnaire. The differences of the brain activation in response to two extreme types of pictures by the two sample t-test were characterized as follows: the activation areas observed in rural scenery over urban were the insula, middle frontal gyrus, precuneus, caudate nucleus, superior parietal gyrus, superior occipital gyrus, fusiform gyrus, and globus pallidus. In urban scenery over rural, the inferior frontal gyrus, parahippocampal gyrus, postcentral gyrus, superior temporal gyrus, amygdala, and posterior cingulate gyrus were activated. The fMRI patterns also clearly show that rural scenery elevated positive emotion such as happiness and comfort. On the contrary, urban scenery elevated negative emotion, resulting in activation of the amygdala which is the key region for the feelings of fear, anxiety and unpleasantness. This study evaluated differential cerebral areas of the human brain associated with rural and urban picture stimulation using a 3.0 Tesla fMRI. These findings will be useful as an objective evaluation guide to human suitability for ecological environments that are related to brain activation with joy, anger, sorrow and pleasure.

Functional Neuroanatomy Associated with Natural and Urban Scenic Views in the Human Brain: 3.0T Functional MR Imaging

OBJECTIVE: By using a functional magnetic resonance imaging (fMRI) technique we assessed brain activation patterns while subjects were viewing the living environments representing natural and urban scenery. MATERIALS AND METHODS: A total of 28 healthy right-handed subjects underwent an fMRI on a 3.0 Tesla MRI scanner. The stimulation paradigm consisted of three times the rest condition and two times the activation condition, each of which lasted for 30 and 120 seconds, respectively. During the activation period, each subject viewed natural and urban scenery, respectively. RESULTS: The predominant brain activation areas observed following exposure to natural scenic views in contrast with urban views included the superior and middle frontal gyri, superior parietal gyrus, precuneus, basal ganglia, superior occipital gyrus, anterior cingulate gyrus, superior temporal gyrus, and insula. On the other hand, the predominant brain activation areas following exposure to urban scenic views in contrast with natural scenes included the middle and inferior occipital gyri, parahippocampal gyrus, hippocampus, amygdala, anterior temporal pole, and inferior frontal gyrus. CONCLUSION: Our findings support the idea that the differential functional neuroanatomies for each scenic view are presumably related with subjects' emotional responses to the natural and urban environment, and thus the differential functional neuroanatomy can be utilized as a neural index for the evaluation of friendliness in ecological housing.

Effect of the Mixture of Thrombin Powder and Gelfoam Powder on Control of Exposed Cancellous Bone Bleeding

No abstract available.

Partial Pediculectomy for Spondylolisthesis with Radicular Pain Combined with Severe Osteoporosis

No abstract available.

Anterior Decompression and Internal Fixation with Anterior Instrument and Surgical Titanium Mesh in Thoracolumbar Unstable Spine Injuries(Long-term Follow-up Results)

No abstract available.

Comparison of Intracranial Ictal EEG Patterns between Medial and Lateral Temporal Lobe Epilepsy / 대한간질학회지

BACKGROUND AND OBJECTIVES: Temporal lobe epilepsy is the most common uncontrolled epileptic condition and is increasingly treated with surgery. In the absence of definitive results from noninvasive procedures, patients undergo implantation of intracranial electrodes. Intracranial EEG recordings are more accurate than scalp EEG recordings because of minimal artifact and closer approximation to the area of seizure onset. Intracranial EEG patterns between the medial and the lateral temporal lobe epilepsy were thought to have a little differences. METHODS: The authors compared the morphological pattern of seizure onset area, spread pattern, termination pattern and duration of the intracranial EEG manifestation of spontaneous seizures recorded from combined depth and subdural electrodes in 25 intractable temporal lobe epilepsy patients. RESULTS: Sixteen cases were medial temporal onset, six cases were neocortical onset and three cases were multifocal onset. The morphological onset pattern of medial temporal seizures was more likely to have high frequency rhythmic discharge (>13 Hz) and tended to show repetitive spikes prior to the seizure, whereas neocortical seizures were characterized by slow (4-to 10-Hz) and fast frequencies (>35 Hz), without evidence of repetitive spikes. The mean ictal duration at seizure onset of complex partial seizure of medial onset seizure was 121 seconds and was not different from those of neocortical seizures which were 115 seconds. Neocortical seizures take more time to propagate than medial seizures. Propagation to the opposite side of neocortical onset seizure takes 45.53 seconds, whereas medial temporal onset seizure takes 27.92 seconds. In case of second generalization, neocortical seizures continued longer than medial seizures. Of the medial onset temporal lobe seizures, except the simple partial seizures, the 35.2% of seizures initially spread to ipsilateral neocortex, and the 28.2% of seizures initially spread to the contralateral medial temporal lobe and the 25% of seizures simultaneously propagated to the ipsilateral neocortex and contralateral medial temporal lobe. Among the seizures initiated from the neocortex, 79.3% of seizures initially spread to the ipsilateral medial temporal area, but never initially spread to opposite neocortex. The termination pattern of seizures was divided into three types according to their location. In case of medial temporal lobe seizures, the mean of 31% of seizures was diffusely terminated , 38% of seizures terminated at the onset region and 38% of seizures were elsewhere within onset region. On the other hand, 48.6% of neocortical temporal lobe seizure were terminated at seizure onset region. CONCLUSIONS: The pattern of ictal intracranial EEG provides distinguishable differences between the medial temporal seizure and the neocortical temporal seizure.

Ependymal Cyst of the Sylvian Fissure

Cerebral ependymal cysts are very rare. About 30 cases have been reported in the literature. They mimic arachnoid cysts clinically and on imaging studies but are different from arachnoid cysts in pathological findings. They are believed to arise by the sequestration of a small segment of the primitive ependymal lining into either the cortical mantle or the perimedullary mesh. They occupy the central white matter of the frontal or temporoparietal lobes. The authors describe a case of septate ependymal cyst involving left sylvian fissure. The clinicopathological features, treatment, and results of previously reported cases are reviewed, and the etiology and pathogenesis of these cysts are discussed.

An Analysis of Results of Surgical Treatment of Epilepsy at National Epilepsy Center in Japan / 대한간질학회지

PURPOSE: The neurosurgical group of the National Epilepsy Center in Japan has been operating on epileptic patients for 17years. In recent 10 years, The 387 patients that have been operated on have enjoyed positive results. in this study, the authors will attempts to make a scheme for surgical treatment of epilepsy based upon the analysis of the patients who were treated with surgery METHODS: THe authors investugated the influenced of advanced in diagnostic procedures. In order to study the relationship between the previous disease and the histologic results, we divided the 152 temporal lobe epilepsy patients who received a resection of both medial temporal structure and lateral neocortex two groups : those with hippocampal sclerosis and those with some other histologic finding. For analysis, patients were divided into 3 groups : first, a lesional group : second, a skip group that had no chronic intractanial recording : third, an intracranial recording group. The results at 2 years, 5 years, 8 years, and 10 years after surgery were studied based on Engel's classification RESULTS & CONCLUSION: With the development of better diagnostic equipment, the incidences of epilepsy surgery have increased, while the percentage of the cases requiring invasive diagnostic procedure has been decreased overall. Not only have the cases of surgery for temporal lobe epilepsy increased but also for extratemporal epilepsy as well. Mesial temporal sclerosis and cortical migration disorder were the most common lesions requiring operative treatment. Febrile status epilepticus in childhood was the most common etiology of epilepsy found. Eighteen children among the twenty-three who had been operated were lesional cases. Longterm follow up studies up studies up to 10 years after surgery shows no worsening in patients condition based on Ecgel's grade of temporal lobe epilepsy.

Analysis on the Early Surgical Results of Patients with Poor-grade Anterior Communicating Artery Aneurysms via Frontotemporal-transorbital Approach

Anterior communicating artery aneurysm is located in the deep area of the brain base around the important midline structure. It has adjacent complex arterial anatomy and multidirectionally projected aneurysm fundus. For these reasons, various surgical approaches including anterior interhemispheric and pterional approaches to the anterior communicating artery aneurysm have been introduced, but none of them are thought to be completely adequate for large and complex anterior communicating artery aneurysm. In the acute stage when brain edema is very severe, poor-grade anterior communicating artery aneurysm is more difficult to treat surgically and represents higher morbidity and mortality. In our hospital, forty one patients with Hunt-Hess grade IV-V anterior communicating artery aneurysms were operated on via frontotemporal-transorbital approach within 72 hours after onset of subarachnoid hemorrhage from May 1, 1990 to April 30, 1996. The frontotemporal-transorbital approach was found to have many advantages in the surgery of these poor-grade anterior communicating artery aneurysms, i.e., providing multidirectional surgical dissection and aneurysmal viewing, mininal brain retraction, wider basal exposure, shortest distance to the lesion, and preservation of the nerve and vascular supply to the frontotemporal muscle. The results of the early surgery for poor-grade anterior communicating artery aneurysm via frontotemporal-transorbital approach represented reduced morbidity(31.7%) and mortality(22.0%).

A Clinical Analysis of Surgically Managed Tuberculous Spondylitis

Fourty three patients with tuberculous spondylitis were surgically treated through the anterior approach at our hospital from January, 1989 to December, 1994. Among them, 32 cases were followed up more than 18 months postoperatively, and were included in this study. The most prevalent location was lumbar region(50%). Paraparesis was frequently seen in patients with middle and lower thoracic spinal lesions and all patients with neurologic deficits improved after decompression of spinal cord. Autogenous rib and/or iliac strut bone grafting was performed, followed by spinal instrumentation. Solid bone fusion was obtained in all patients. There was no need for prolongation of duration of antituberculous drug therapy and no increased incidence of secondary infection due to spinal instrumentation.

Surgical Management of Patients with Isthmic Spondylolisthesis with Transpedicular Screw Fixation and Posterior Lumbar Interbody Fusion using Posterior Movable Segment

Twenty three patients with isthmic spondylolisthesis were operated on from December 1993 to June 1995. There were 14 female and 9 male patients and the average age of the patients was 50(ranging 20-67) years old. Symptoms in the lower extremities had been present for 3 months to 10 years, although varying degrees of back pain had existed for longer periods. Disability was caused mainly by claudication in 20 patients. Diagnostic studies included plain films, tomography, CT scaning, and MRI. Single interspace was involved in 18 patients, and in five patients, two interspaces were involved. After wide decompression and discectomy, stabilization was reestablished by segmental pedicular screw fixation device(Diapason(R) pedicular system) and interbody fusion using posterior movable segment as graft material. Between 6 to 24 months postoperatively, all patients exhibited radiographic fusion. The results were excellent in 12 cases, good in 8 cases and fair in 3 cases. The authors believe that full four nerve roots decompression, pedicular screw fixation. Posterior lumbar interbody fusion using movable segment as graft material, and prevention of nerve root traction injury during insertion of graft bone are important points to get good post-operative results.

Clinical Analysis of Patients with Thoraco-lumbar Spinal Lesions Managed by Vertebrectomy, Interbody Fusion and Stabilization using Kaneda Device

Among the 98 patients who underwent operations for thoracolumbar spinal lesions from May 1989 to September 1994, the authors performed clinical analysis of 72 patients who were followed-up for more than 12 months. There were 52 cases of trauma, 18 cases of tuberculous spondylitis, and 2 cases of metastatic tumor. After partial or toal vertebrectomy, interbody fusion was performed using autogenous iliac bone or autogenous ribs which were taken while approaching the thoracic spine, and stabilized using Kaneda devices. Complete neural decompression was possible under direct vision in all cases. Neurologic deficits improved to an average of 1.7 grades using a modified Frankel scale. Patients with tuberculous spondylitis did not show recurrence or any evidence of increased risk of secondary infection caused by instrumentation. Loosening or breakdown of instruments occurred in 4 patients, and spinal deformity in 7 patients, but reoperation was not needed in any of these patients. By anterior decompression, interbody fusion and stabilization using Kaneda device in thoracolumbar spinal lesions, we could obtain satisfactory neurologic improvement as well as immediate firm stability and high fusion rate involving only a minimum(usually two) number of motion segments as compared with the posterior approach.