Advance of studies on interaction between active components of natural medicines and lysozymes / 中国中药杂志

Lysozyme (LYSO), as an alkalescent protein micromolecule in living organisms, exhibits important pharmacological actions such as antibiosis, anti-inflammatory, antivirus and enhancing immunity. LYSO can combine with many exogenous and endogenous substances and carry many drugs. This essay summarizes interaction between different kinds of active components of natural medicines and lysozymes, which is significant to comprehensively understand pharmacological mechanism of natural drugs and their transfer and metabolic process in organisms, optimize molecule structures of drugs and increase bioavailability and biological effects of natural drugs.

Effect of BMI and WHR on lumbar lordosis and sacrum slant angle in middle and elderly women / 中国骨伤

<p><b>OBJECTIVE</b>To investigate the effect of body mass index (BMI) and waist hip ratio (WHR) on lumbar lordosis and sacrum slant angle in the patients with low back pain, and to discuss the theory of low back pain induced by obesity.</p><p><b>METHODS</b>The Roland Disability Questionnaire (RDQ) was answered by 98 middle and elderly women with low back pain, whose body height, body weight, waist circumference, and hip circumference were measured and used to calculate their MBI and WHR. According to BMI, all the cases were divided into normal, overweight and obesity groups. These cases were also divided into noncentral and central obesity groups according to WHR. The lateral X-ray films of the lumbar spine were studied by measuring LCI, Cobb angle, and SSA. The data of all groups were analyzed statistically.</p><p><b>RESULTS</b>LCI, Cobb angle, SSA and RDQ scores in the overweight and obesity groups are significantly higher than those in the normal group. LCI, Cobb angle, SSA, and RDQ scores in the central obesity group are significantly higher than those in the noncentral obesity group.</p><p><b>CONCLUSION</b>BMI exceeding 24 kg/m2 or WHR exceeding 0.85 may increase the measurements of Cobb angle, SSA and RDQ scores. Low back pain may occur because of overweight, obesity, or central obesity. The anatomy foundation of the increasing lumbar lordosis and sacrum slant angle may be the one of reasons of low back pain in obese person.</p>