Efficacy of endoscopic submucosal dissection for colorectal submucosal tumors / 中国内镜杂志

Objective To evaluate the outcomes and safety of ESD in colorectal SMTs. Methods Between January 2011 and January 2017, we performed ESD on 68 consecutive colorectal SMTs in 67 patients. We evaluated the clinical outcomes of all said cases. Results The most common type of the 68 colorectal SMTs was neuroendocrine tumor (42/68, 61.8%), followed by lipoma (20/68, 29.4%). Most of neuroendocrine tumors (41/42) were located in rectum, and most of lipomas (18/20) were located in colon. Among the 46 tumors which were evaluated by endoscopic ultrasonography (EUS) before ESD,38 tumors (82.6%) were located in the submucosal layer, and 31 tumors (67.4%) were hypoecho. Our overall endoscopic en bloc resection rate was 100.0%, and our R0 resection rate was 94.1% respectively. Our perforation rate of ESD was 6.0%, delayed bleeding rate 1.5%. None of the patients need surgical intervention because of complication. Follow-up rate was 95.5%, no recurrence or metastasis was observed during the median follow-up period 33 months (range 3~75 months). Conclusion EUS is conductive to the diagnosis of colorectal SMTs before ESD. ESD is a safe and effective treatment for colorectal SMTs.

Endoscopic submucosal enucleation for gastric submucosal tumors originated from muscularis propria layer: clinical analysis of 116 case / 中华胃肠外科杂志

<p><b>OBJECTIVE</b>To explore the efficacy and safety of endoscopic submucosal enucleation (ESE) for gastric submucosal tumors (SMTs) originated from muscularis propria.</p><p><b>METHODS</b>A total of 116 patients with gastric SMT originated from muscularis propria underwent ESE in Department of Gastroenterology of the Taizhou Hospital between July 2006 and March 2011. The occurrence of intra-operative and post-operative complications and corresponding treatment were recorded. After the treatment of ESE, the patients were followed up endoscopically.</p><p><b>RESULTS</b>The success rate of operation was 96.6%. The mean time of the procedure was (51.9±16.3) min. Complications included intra-operative bleeding (n=9, 7.8%), perforation (n=20, 17.2%), and post-operative bleeding (n=3, 2.6%). Among them, 5 cases (4.3%) required surgical intervention. None of patient had other complications such as peritoneal abscess or peritonitis. The mean hospitalization time after ESE was 6.1 days. The median follow-up period was 12 months (range, 3-48 months) and there was no residual tumor or recurrence.</p><p><b>CONCLUSION</b>ESE is a safe and feasible treatment for patients with gastric SMT originated from muscularis propria.</p>