ABSTRACT
<p><b>OBJECTIVE</b>To investigate the situation of dog rabies and analyze it's relationship with human rabies.</p><p><b>METHODS</b>In Guizhou, Guangxi and Hunan provinces which suffered from rabies most heavily, one or two cities were selected respectively from regions with high-, middle-, low-incidence rate of human rabies as investigation spots where Dogs' brain specimens were collected and detected with both direct immunofluorescence assay (IFA) and RT-PCR.</p><p><b>RESULTS</b>A total of 2887 specimens were collected and 66 of these were positive for IFA and RT-PCR. Therefore, the rate of positive specimens was 2.3%. However, there was not a close relationship in the incidence rate of dog rabies and human rabies.</p><p><b>CONCLUSION</b>Dog's infection situation of rabies contributed to the severe epidemic of human rabies.</p>