ABSTRACT
@#AIM: To study the application value of digital and visual retinoscope in the detection of ametropia in adolescents.<p>METHODS:A retrospective analysis of digital visual inspection and traditional retinography test results of 69 adolescents in the ophthalmology department of our hospital from January 2019 to October 2019. SPSS 20.0 software analyzed the correlation of spherical equivalent, diopter of cylindrical power and axial direction measured by two detection methods. Taking the clinical examination results as the control, the diagnostic value was compared. <p>RESULTS: There was no statistically significant difference in the measuring of spherical equivalent, diopter of cylindrical power and axial direction between digital and visual retinoscope and traditional retinography(<i>t</i>=0.081, 1.778, 0.983, <i>P</i>=0.935, 0.077, 0.327). And there was a significant positive correlation(<i>r</i>=0.745, 0.572, 0.941,<i> P</i><0.01). At the same time, two detection methods have the same sensitivity. Digital and visual retinoscope higher than traditional retinography at the specificity, accuracy, positive predictivevalue and negative predictive value.<p>CONCLUSION: The detection of ametropia in adolescents with digital and visual retinoscope has a good correlation with traditional retinography. Compared with the latter, the former has improved for the diagnosis of ametropia, which deserves clinical attention.
ABSTRACT
@#AIM: To investigate the efficacy of autologous serum combined with recombinant human epidermal growth factor in repairing of corneal defect after corneal foreign body eliminating operation.<p>METHODS: Totally 92 patients with corneal foreign body(110 affected eyes)as the research object in our hospital from October 2015 to March 2016. All the patients were divided into the treatment group and the control group according to the random number table. There was no significant difference between the two groups in age, sex and disease course. Both groups received corneal foreign body elimination by slit lamp. The treatment group was given eye drops containing epidermal growth factor combined autologous serum and tobramycin after surgery, while the control group was only administrated with epidermal growth factor and tobramycin. Treatment effects were compared 1wk after treatment.<p>RESULTS: One week after the treatment, the cure rate in the treatment group(96.4%)was much higher than that in the control group(78.2%). Two days after treatment, the fluorescein staining in the treatment group was 98.2%, it was higher than that in the control group(83.6%). The concentration of TNF-α and IL-6 of the treatment group was lower than that in the control group. One week after the treatment, AS-OCT images showed that the repair of corneal matrix in the treatment group was closer to the preoperative normal level.<p>CONCLUSION: The treatment effect that AS combined rhEGF is much better than that only usde rhEGF, shortened healing time of corneal epithelial wound. It is more effective and security to treat traumatic corneal epithelial defect, better repair function to corneal matrix.