ABSTRACT
<p><b>OBJECTIVE</b>To observe the clinical effect of a combined therapy in the treatment of simple premature ejaculation.</p><p><b>METHODS</b>A total number of 110 patients with simple premature ejaculation were divided into a control group (n = 50), given oral hydrochloric acid sertraline only, and a combined therapy group (n = 60), treated by oral administration of hydrochloric acid sertraline, local inunction of a traditional Chinese medicine and guidance in sexual psychology and knowledge. At the end of a 4-week treatment and 4 weeks after the drug withdrawal, the therapeutic effects were evaluated by ejaculation latency and satisfaction with sexual life.</p><p><b>RESULTS</b>The total effectiveness rates at the end of the 4-week treatment were 91.6% and 76% in the combined therapy and the control groups, while those 4 weeks after the drug withdrawal were 68.3% and 42% respectively, both with significant differences in between (P < 0.05 and P < 0.01).</p><p><b>CONCLUSION</b>The combined therapy has a satisfactory clinical effect and stability in the treatment of simple premature ejaculation.</p>