ABSTRACT
<p><b>OBJECTIVE</b>To explore the clinical significance of early diagnose and treatment of subclinical renal allograft rejection.</p><p><b>METHODS</b>Ninety-six renal allograft recipients (54 male and 42 female) with normal renal function aged 17 to 58 years (mean 37.5 years) were included in this study. Early subclinical rejection was diagnosed 3 months after the transplantation by color Doppler examination.</p><p><b>RESULTS</b>Patients with early subclinical rejection were given methylpredisolone followed by adjustment of immunosuppressive regimens, and no difference was observed in 3-year survival rate between these patients and those with normal renal allograft findings.</p><p><b>CONCLUSION</b>Early diagnosis and treatment of subclinical renal allograft rejection is significant to improve renal allograft survival rate.</p>