ABSTRACT
Thioredoxin is one of important disulfide bond reductases in cells ,which plays important role in antioxi‐dant stress of cells and maintaining reduced state of intracellular protein and its normal functioning .The present ar‐ticle set forth the possible biological function of thioredoxin in atherosclerosis from its antioxidation ,anti－apopto‐sis ,anti－inflammation and regulation of blood lipid and glucose metabolism etc .,aiming at providing new targets for prevention and treatment of atherosclerosis .
ABSTRACT
Metabolic syndrome (MS)is a clinical syndrome featured by glucose and lipid metabolic disorders,hyper- tension and obesity etc.,whose key links are insulin resistance and abdominal obesity.MS is closely related with cor- onary atherosclerosis,every link of MS can lead to occurrence and development of atherosclerosis.The present arti- cle mainly stated research progress of the correlation between MS and coronary atherosclerosis in recent years.
ABSTRACT
The present study used optical coherence tomography (OCT) to observe the relationship between inhibitor of monocyte chemoattractant protein-1 (MCP-1) and coronary in-stent restenosis after stenting ,and proved that MCP-1 is a key inflammatory factor causing in-stent restenosis after stenting .
ABSTRACT
The most important characteristic of optical coherence tomography (OCT)is high resolution (about 10~15μm),so it can perform high resolution cross section tomography on internal microstructure of biological tissue. From 2000 OCT first used to detect coronary artery lesions,it already gradually popularized in diagnosis and treat-ment field of coronary artery intervention,It has become a main method for intravascular detection,diagnosis and guiding treatment of coronary diseases.