ABSTRACT
Two groups of male adult rats were fed with rations containing 10% protein, and another two groups with 5% protein. One group of each protein level was inflicted with 20% body surface area burn, and another pair-fed group served as control. The serum total protein and albumin were significantly lowered after burn, while the ?-and ?-globulins were significantly elevated. The changes of serum free amino acids were variable on the first post-burn day, as Serine, Tyrosine, and Tryptophan were reduced, but Alanine, Methionine, and Arginine were elevated. One week after the injury, most amino acids were remarkably reduced, with c(?)(?) Melhionine remaining higher.
ABSTRACT
Objective: Three experiments were used to evaluate the effects of zinc deficiency on growth, learning and memory ability of rats. [WT5FZ]Methods: In experiment Ⅰ and experiment Ⅱ, the experimental rats were divided into three groups, which were zinc deficiency group (ZD), pair fed group (PF), and zinc deficiency and supplementation group (ZS). Their durations were 35 days and 28 days respectively. In experiment Ⅲ, the experimental rats were divided into ZD, PF and ad libitum (AL) group. Results: Zinc deficiency significantly decreased the growth and learning ability of rats, whereas zinc supplementation reversed the above status. Conclusion: The results suggest that zinc not only influence growth, but also the advanced function like learning and memory ability of brain.
ABSTRACT
Objective:[WT5BZ]The effect of different contents of zinc in feed on learning and memory function and brain somatostatin,zinc and calcium concentrations in rats were studied. [WT5HZ]Methods:[WT5BZ]The feeds contained 20, 50, 100, 200, 400, 800 mg/kg zinc respectively.The learning and memory function of animals were determined by radioimmunoassay.Their zinc and calcium contents were determined by atomic absorption spectrophotometry. [WT5HZ]Results:[WT5BZ]Feeds containing 100 and 200 mg/kg zinc were adequate for learning and memory function of rats,whereas other feeds resulted in poor learning and memory function,and depression in somatostatin concentration in hypothalamus,hippocampus and cerebrum cortex.Additionally,feeds containing lower than 100 mg/kg zinc decreased zinc concentrations in blood,hippocampus,cerebrum cortex and hypothalamus,and calcium concentration in cerebrum cortex. [WT5HZ]Conclusion:[WT5BZ]These results suggest that 100 200 mg/kg zinc in feed is adequate for maintaining learning and memory function in rats.
ABSTRACT
The selenium levels in plasma and liver of rats suffered from 3rd degree burn of 20% BSA on dorsum were significantly decreased, plasma VE dropped too, while the VE contents of RBC and liver were as high as those in control group. After giving 2.3?g selenium/100g bw as selenite to the burned rats, the VE contents of RBC and liver as well as plasma were then decreased as compared with control. The content of plasma total sulfhydryl group decreased more in selenium-supplemented group than in burned control.These results indicated that the requirement of VE probably increased after supplementation of selenium in burned rats.
ABSTRACT
The study includes 2 experiments. Experiment 1: 24 male weanling Wistar rats were divided into 3 groups, with 8 rats in each group:zinc-deficient group (ZD), pair-fed group (PF), zinc-sufficient group (ZS). The experiment term was 30 days, and the items observed were feed intake, body weight, serum zinc, tibia zinc, serum vitamin A and liver vitamin A. The results showed that Zn-deficient rats could not mobilize liver vitamin A into their blood normally. Experiment 2; 40 male weanling Wistar rats were raised with Zn-deficient feed for 30 days, then they were divided into 4 groups randomly, keeping 7 rats in each group:Zn-deficient group (ZD), Zn-treatment group I(ZT1), Zn-treatment group II(ZT2), Zn-treatment group III(ZT3), their daily Zn dosages were 0.63 umol, 1,89 umol, 3.80 umol respectively. The treatment lasted for 6 days. The results demonstrated that serum zinc and vitamin A concentrations of the 3 Zn-treated groups were much higher than that of ZD group. In contrast, their liver vitamin A concentrations were much lower than that of ZD group.