ABSTRACT
Cathepsin S(Cat S) is an important member of the cysteine cathepsin protease family.It is a lysosomal protease, which has been shown to be expressed in inflammatory conditions and autoimmune diseases.It has more specific roles such as antigen presentation, tissue repair, cell proliferation and apoptosis.It contributes to a variety of clinical diseases.In this review, we summarize the structure, characteristics and functions of cathepsin S in kidney and rheumatic diseases.
ABSTRACT
Cathepsin S (Cat S) is an important member of the cysteine cathepsin protease family.It is a lysosomal protease,which has been shown to be expressed in inflammatory conditions and autoimmune diseases.It has more specific roles such as antigen presentation,tissue repair,cell proliferation and apoptosis.It contributes to a variety of clinical diseases.In this review,we summarize the structure,characteristics and functions of cathepsin S in kidney and rheumatic diseases.
ABSTRACT
The etiology and pathogenesis of nephrotic syndrome is not fully clear.Most pepole believe that it is associated with the disorder of immune function.As immunoregulatory factors,interleukins(IL) and interferon(IFN) are closely related with the onset of nephrotic syndrome.In this paper,we review the role of IL-21 and INF-γin pathogenesis of nephrotic syndrome.
ABSTRACT
Objective To investigate publication of papers by nursing staff in a TCM hospital and to find out the problems as well as countermeasures.Method A retrospective analysis about authors,education,academictitle,length of service and age was done to investigate the classes of published papers from 2008 to 2012.Results The academic publication by the nurses from 2008 to 2012 was increased.Among these articles,the TCM nursing techniques took up the largest ratio,which accounted for 29.12%. There were significant differences in ages,length of service and educational background in authors(P<0.05).Conclusions Nurses’ awareness and capabilities of publishing academic papers needs enhancement as well as training.It may be significant to strengthen their incentives in scientific research by enforcing encouraging policies.