ABSTRACT
Objective:To build an evaluation index system for linac stability and establish a scientific, systematic and objective evaluation standard for the stability of linac equipment.Methods:Based on the Delphi and AHP methods, a three-level index system for the stability of linac equipment was established, and the correlation coefficients and weights were calculated using Microsoft Excel 2007 and SPSS 16.0.Results:The enthusiasm of experts in two rounds was 85%(17/20) and 92%(23/25), the authority coefficients were 0.79 and 0.87, and the expert Kendall coordination coefficients were 0.957(first-level index, P<0.05), 0.637(second-level index, P<0.05) and 0.527(third-level index, P<0.05), respectively. Finally, a three-level index system covering 2 first-level indicators of mechanical treatment system and accessory system, 9 second-level indicators and 32 third-level indicators was established. The CVs of all levels of indicators were less than 0.25 and passed the consistency test. Conclusion:The evaluation index system for linac equipment stability has good scientificity, operability and versatility, which can provide theoretical and quantitative reference for linac stability evaluation and equipment purchase.
ABSTRACT
Taxol could induce tumor cell apoptosis throug h activation of Fas/FasL and caspases. bcl-2 also played an important role in t axol-induced cell apoptosis. Furthermore, taxol had the similar action with lip opolysaccharide on inducing the release of bioactive substances including tumor necrosis factor, interleukin and nitric oxide. There were as well some progresse s in taxol-resistance of tumor cells.