ABSTRACT
A microscopic examination of an appropriately prepared and well-stained blood smear by a knowledgeable laboratory professional is necessary and clinically useful in a number of circumstances and for a variety of reasons. In this article, an attempt is made to delineate the purpose and criteria for blood smear examination in a variety of circumstances that are encountered in everyday laboratory hematology practice. A blood smear scan serves to at least (a) verify the flagged automated hematology results and (b) determine if a manual differential leukocyte count needs to be performed. Blood smear examination/manual differential leukocyte count with complete blood count (CBC) provides the complete hematologic picture of the case, at least from the morphologic standpoint. Blood smear review with or without interpretation serves to ensure that no clinically significant finding is missed, besides providing diagnosis or diagnostic clue(s), particularly if and when interpreted by a physician.
Subject(s)
Humans , Blood Cell Count , Hematologic Tests/methods , Leukocyte Count , Leukocytes/cytology , Medical Laboratory Personnel/standardsABSTRACT
Mannitol is a kind of major marine bio-products with important biological activities. It is not only used in injection as raw material, but also used with other medicine as supplemental composition. Simultaneously, it is used for synthesis of a series of derivative medicines. The specific application of mannitol as raw materials and excipient was reviewed in detail. And the synthetic methods, properties and medical application of every derivative medicine were introduced.