ABSTRACT
Objective To explore risk factors for healthcare-associated infection (HAI)in patients undergoing craniocerebral operation,and provide guidance for the prevention of HAI in patients in department of neurosurgery. Methods 200 patients who underwent craniocerebral operation in a department of neurosurgery from November 2013 to November 2014 were surveyed,risk factors for HAI were analyzed.Results Among 200 patients undergo-ing craniocerebral operation,81 patients developed 99 cases of HAI,HAI rate was 40.50%,HAI case rate was 49.50%;the top five HAI sites were lower respiratory tract,urinary tract,intracranial site,bloodstream,and in-testinal tract.Univariate analysis showed that patients’age ≥60,Glasgow Coma Scale (GCS)<15,intraoperative blood loss ≥800 mL,staying in intensive care unit(ICU),indwelling gastric tube,ventricular drainage,using ventilator,tracheotomy,and using H2 receptor antagonists were important risk factors for HAI in patients undergo-ing craniocerebral operation (all P <0.05).Multivariate logistic regression analysis showed that patients’age ≥60, GCS<15,staying in ICU,and using H2 receptor antagonists were independent risk factors for HAI in patients un-dergoing craniocerebral operation.Conclusion Strengthening the surveillance of HAI patients undergoing cranioce-rebral operation and realizing risk factors for HAI are helpful for taking comprehensive prevention measures and re-ducing the incidence of HAI.
ABSTRACT
<p><b>BACKGROUND</b>To investigate the incidence of lung cancer and the trend of the incidence in Wuzhou.</p><p><b>METHODS</b>Based on the lung cancer patients' data collected in Wuzhou from 1981 to 2000, statistical analysis of the lung cancer incidence rates was performed, the lung cancer incidence rates for age-groups and for periods of time were calculated, and the incidence rates for different periods were compared. Using standard world populations the standardized incidence rates of lung cancer and the intercept standardized rate were also calculated.</p><p><b>RESULTS</b>The lung cancer incidence rate was high in Wuzhou. The lung cancer accounted for 21.65% (1 264/5 838) of all cancers. From 1981 to 2000, the incidence rate of lung cancer in Wuzhou increased markedly (P < 0.001); the incidence rate for males increased by 88.43% from 25.33×10⁻⁵ to 47.37×10⁻⁵ ; the rate for females rose by 121.22% from 10.12×10⁻⁵ to 24.66×10⁻⁵ . So was the standardized incidence rate. The median age for the male was 64.5 years old, while the median age for the female was 65.6. 88.8% of the patients were in the age of 55-year-old or more</p><p><b>CONCLUSIONS</b>The lung cancer incidence rate in Wuzhou is high, and the incidence is significantly increased. Therefore, preventing lung cancer is one of the main cancer prevention tasks in Wuzhou.</p>