Clinical efficacy of single center intracavitary isolation procedure for treatment of elderly Standford type B aortic dissection / 中华老年医学杂志

Objective To evaluate clinical efficacy of single center intracavitary isolation procedure for treating elderly Standford type B aortic dissection.Methods 46 consecutive patients aged ≥ 65 years with Standford B aortic dissection,who underwent membrane stent intracavitary isolation treatment,in Tianjin Chest Hospital between 2010-2015 were enrolled in this study.All enrolled patients received examinations of echocardiography,contrast-enhanced CT,hepatic and renal functions,and the blood and urine routine tests before the procedure.After the procedure,the contrastenhanced CT of whole aorta was annually rechecked for all patients in the four time points of predischarge,3,6,12 months after operation.Deadline date of the follow up was December 2015.The outcomes of whole aorta CT and survival rate were analyzed.Results Successful stent implantation was performed in all patients (100 ％).Two (4.3 ％) patients died in the perioperative period,and one died due to the new aortic dissection at the last 8 months after operation.Overall survival rate was 89.1％(41 cases)during the follow-up period(95％CI:52.5-63.6 and 32.6-38.9,all P＜0.05).Conclusions The short and long term outcomes of intracavitary isolation procedure for treating Standford B aortic dissection are satisfactory in elderly patients.Perioperative blood pressure control,strict image measure,and carefully selecting the appropriate scaffold model are the keys for successful operation.

Advances in research of miRNA and ovarian cancer / 肿瘤研究与临床

MicroRNA(miRNA)constitute a large family of small,approximately 21 to 23 nucleotide-long,non-coding RNA that is a key post-transcriptional regulators of gene expression.By base pairing to mRNA,miRNA mediate translational repression or miRNA degradation.The recent study find that miRNA play an important role in carcinogenesis.Here is a reviews of the research advances of miRNA and ovarian cancer.

Prevention of postpartum bleeding of elective cesarean section by misoprestol / 中国医师进修杂志

0.05).Conclusion Oral misoprostol alone is as effective as oxytocin alone for the prevention of postpartum hemorrhage.It is less effective than oral misoprostol plus oxytocin.Misoprostol is applicable for high risk pregnancy with some vascular changes.