ABSTRACT
<p><b>OBJECTIVE</b>To investigate dissolution properties among different components with various polarities and to distinguish these groups from each other.</p><p><b>METHOD</b>Ultraviolet fingerprint spectra (UV FPS) of the components from Baishao (Radix Paeoiae Alba) and Gancao (Radix Glycyrrhizae) with various proportions, extracted with chloroform, ethanol and water successively, were obtained. The analysis was performed on the absolute and relative absorptions of peaks in UV FPS.</p><p><b>RESULT</b>Dissolutions in different rates and in synergy among chemical components were observed, by which different components can be distinguished.</p><p><b>CONCLUSION</b>Dissolution kinetics and processes of the various chemical components from medicinal herbs are of great difference.</p>
Subject(s)
Chloroform , Drug Combinations , Drugs, Chinese Herbal , Ethanol , Glycyrrhiza , Chemistry , Paeonia , Chemistry , Plant Roots , Chemistry , Plants, Medicinal , Chemistry , Quality Control , Reproducibility of Results , Solubility , Spectrophotometry, Ultraviolet , Methods , WaterABSTRACT
<p><b>OBJECTIVE</b>To investigate a new method for the analysis of IR fingerprint spectra of Radix Glycyrrhizae.</p><p><b>METHOD</b>Two indexes, common peak ratio and variation peak ratio, are used to compare the IR spectra of various Radix Glycyrrhizae samples, and the values are calculated by means of sequent analysis.</p><p><b>RESULT AND CONCLUSION</b>The dual-index sequence method provides a good approach to discriminate Radix Glycyrrhizae samples of different species and geographical origins.</p>