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Indian J Physiol Pharmacol ; 1990 Apr; 34(2): 130-2
Article in English | IMSEAR | ID: sea-106764

ABSTRACT

The local analgesic efficacy of EMLA Cream (a eutectic mixture of lidocaine and prilocaine; Astra Pharmaceuticals, Sweden) in reducing the pain at Venous cannulation was investigated in a randommized blind study in 75 children scheduled for elective surgery. In 25 children placebo cream and in 50 children, EMLA cream was applied at the site of venous cannulation 1 hour prior. EMLA Cream was found to be highly effective (84% patients in contrast to 16% patients in placebo group; P less than 0.005). Local side effects of EMLA Cream were negligible.


Subject(s)
Anesthetics, Local/therapeutic use , Anxiety/psychology , Catheterization, Peripheral/adverse effects , Child , Child, Preschool , Drug Combinations , Female , Humans , Infant , Lidocaine/therapeutic use , Male , Occlusive Dressings , Pain/prevention & control , Premedication , Prilocaine/therapeutic use
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