ABSTRACT
Introduction: Gastrinoma is a rare gastrin secretingneuroendocrine tumor. Clinical manifestations are nonspecificgastrointestinal (GI) symptoms or as Zollinger EllisonSyndrome(ZES) which often delays the diagnosis in majorityof patients. Hence a high clinical index of suspicion iswarranted in patients who present with nonspecific GIsymptoms to rule out gastrinoma.Case report: We report a case of 55 year old female whopresented with long standing dyspepsia and chronic diarrhoeaand was diagnosed with Sporadic Duodenal Gastrinomaon detailed evaluation. She was treated with surgicalresection and pathologically diagnosed as well differentiatedneuroendocrine tumor, Gastrinoma – grade I after IHCanalysis. Patient was relieved of her symptoms and becameeugastrinemic after surgery.Conclusion: Any patient with refractory dyspepsia associatedwith long standing non specific abdominal symptoms shouldbe evaluated for Gastrinoma and treated accordingly to avoidmisdiagnosis and complications in the long run.