ABSTRACT
Poroid hidradenoma is a benign tumor that is classified as a poroid neoplasm, and is so called because of its morphology, which is intermediate between the cytological features of a poroid neoplasm (poroid and cuticular cells) and the architectural features of a hidradenoma (solid and cystic areas, and tumor cells restricted to the dermis). As these tumors are cystic and superficially located, fine needle aspiration cytology has been useful, but the diagnosis relies on the histological examination. A 79-year-old woman presented with a solitary walnut-sized, soft, tender, reddish-to-bluish nodular lesion that had been enlarging steadily over a period of two years. Histopathologic examination of the cutaneous lesion showed a well-demarcated tumor composed of poroid and cuticular cells in the dermis not connected to the overlying epidermis, consistent with poroid hidradenoma. Herein, we present a rare case of poroid hidradenoma arising in an unusual location.
Subject(s)
Aged , Female , Humans , Acrospiroma , Biopsy, Fine-Needle , Dermis , Diagnosis , Epidermis , PoromaABSTRACT
Leser-Trelat sign is a rare paraneoplastic dermatosis that is characterized by the eruptive and rapid development of multiple seborrheic keratosis that coincides with an internal malignancy. Eruptive seborrheic keratosis can be pruritic and appear in a "Christmas-tree pattern." This sign occurs in association with a number of cancers, such as adenocarcinoma of the gastrointestinal tract and various lymphoproliferative disorders. However, Leser-Trelat sign associated with a malignant melanoma is very rare. A 58-year-old male patient presented with an asymptomatic black mass on the penile orifice and patch on the glans penis. He complained of gross hematuria. At the same time, he developed asymptomatic multiple brown papules and plaques on the back. The histopathologic findings of the glans and back lesions were consistent with malignant melanoma and seborrheic keratosis, respectively. Here, we describe a rare case of Leser-Trelat sign associated with malignant melanoma.
Subject(s)
Humans , Male , Middle Aged , Adenocarcinoma , Gastrointestinal Tract , Hematuria , Keratosis, Seborrheic , Lymphoproliferative Disorders , Melanoma , Penis , Skin DiseasesABSTRACT
BACKGROUND: Dermoscopy is a real-time, noninvasive technique that increases the diagnostic accuracy of clinical evaluation by the dermatologist. Characterization of facial actinic keratosis via dermoscopy is valuable in guiding the dermatologist in the differential diagnosis of facial skin lesions. To our knowledge, dermoscopic evaluation of actinic keratosis has not yet been reported in Korean literature. OBJECTIVE: The purpose of this study was to investigate the dermoscopic features of facial actinic keratosis in Koreans. METHODS: We examined 60 patients with facial actinic keratosis using dermoscopy. We determined the frequency of specific features revealed by dermoscopy across the Korean patient population and compared our results with those of other published studies. RESULTS: A total of 67 facial actinic keratoses were observed in 60 patients. The common features of non-pigmented actinic keratoses revealed by dermoscopy were a red pseudo-network (66%), white-to-yellow surface scales (48.9%), linear wavy vessels (38.3%), and targetoid hair follicles (42.6%). The common features of pigmented actinic keratoses revealed by dermoscopy were slate-grey dots (55%) and globules (30%), annular-granular pattern (35%), a brown-to-gray pseudo-network (40%), and targetoid hair follicles (30%). The frequency of specific features revealed by dermoscopy across the analyzed patient population was not significantly different from that reported in other studies, except for rhomboidal structures (5%), which was lower in Koreans than in other populations (35.8%, p<0.05). The frequency of dermoscopic features was different according to histopathologic subtypes (hypertrophic, atrophic, bowenoid, acantholytic actinic keratosis). CONCLUSION: Dermoscopy revealed specific features of facial actinic keratosis that can be utilized to evaluate and diagnose facial skin lesions.
Subject(s)
Humans , Actins , Dermoscopy , Diagnosis, Differential , Hair Follicle , Keratosis, Actinic , Skin , Weights and MeasuresABSTRACT
Erythema annulare centrifugum is an inflammatory skin disorder of unknown etiology characterized by erythematous urticarial papules that enlarge in a centrifugal pattern to form annular appearance. These lesions are usually asymptomatic. Erythema annulare centrifugum generally tends to be a chronic condition. It develops most frequently in adults between 30 and 50 years of life, and only a few infantile cases have been reported in the English literature. Herein, we present an additional case of infantile erythema annulare centrifugum with a review of the literature.
Subject(s)
Adult , Humans , Infant , Erythema , SkinABSTRACT
Crohn's disease is a systemic inflammatory and granulomatous disease, mainly involving the gastrointestinal tract with extraintestinal manifestations such as the skin, liver and bone. Cutaneous manifestations of Crohn's disease are relatively common; however, the groin is an unusual site for cutaneous Crohn's disease. A 36-year-old male presented with mild pruritic nodules on the left groin for 2 months. Nine years ago, he was diagnosed with intestinal Crohn's disease by endoscopic biopsy. Histopathologic examination of the cutaneous lesion showed non-caseating granulomatous reactions composed of multinucleated giant cells with lymphohistiocytic infiltration in the dermis. Staining for periodic acid-Schiff and acid-fast bacilli was negative. From these findings, we diagnosed these lesions as cutaneous Crohn's disease. The lesions were markedly improved with three rounds of intralesional steroid injection.
Subject(s)
Adult , Humans , Male , Biopsy , Crohn Disease , Dermis , Gastrointestinal Tract , Giant Cells , Groin , Liver , SkinABSTRACT
Poikiloderma is a combination of telangiectasia, irregular mottled hyperpigmentation/depigmentation and superficial atrophy in a reticular pattern. Poikiloderma of Civatte is a rather common, acquired poikiloderma of the face and neck, most often affecting the middle-aged or the elderly. Poikiloderma of Civatte runs a chronic, benign, but irreversible course. The ideal treatment is elimination of both the vascular and pigmented components simultaneously. Most methods to treat this condition are ineffective, inefficient, or inconvenient and may cause significant side effects such as depigmentation and scarring. Recently, intense pulsed light sources have been used in poikiloderma of Civatte with their ability to target vascular and pigment components simultaneously. We experienced two cases of poikiloderma of Civatte treated by intense pulsed light with different parameters than those used in former reports, so we report this case with a review of previously published cases.
Subject(s)
Aged , Humans , Atrophy , Cicatrix , Light , Neck , Telangiectasis , ThoraxABSTRACT
An 82-year-old woman presented with a 5-year history of erythematous to brown patches and plaques on both legs, arms and trunk. Histopathological findings of biopsy specimens were consistent with mycosis fungoides, and the tumor cells were positive for CD3 and negative for CD20 in immunohistochemical stain. Imaging studies proposed the suspicion of ureter cancer, and the result of cystoscopic biopsy showed papillary urothelial carcinoma. Mycosis fungoides is the most common type of cutaneous T-cell lymphoma, characterized by variable cutaneous manifestations, including patches, plaques, tumors, and erythroderma. There were several studies concerning the evaluation of the second malignancy risk after cutaneous T-cell lymphoma, however the relationship between mycosis fungoides and ureter cancer is not revealed. This patient is considered a case of mycosis fungoides with coincidental ureter cancer.
Subject(s)
Aged, 80 and over , Female , Humans , Arm , Biopsy , Dermatitis, Exfoliative , Leg , Lymphoma, T-Cell, Cutaneous , Mycosis Fungoides , Neoplasms, Second Primary , Ureter , Ureteral NeoplasmsABSTRACT
Lichen planus pigmentosus (LPP) is a rare variant of lichen planus, and it is characterized by hyperpigmented, dark brown to violaceous colored macules or patches on the sun exposed areas of the skin. The term of LPP-inversus was proposed to describe some cases with LPP arising on the intertriginous areas. Clinically, LPP-inversus is characterized by well defined dark brown to violaceous macules or patches with minimal symptoms and it is predominantly confined on the flexural areas. The histological characteristics are a lichenoid inflammatory infiltrate on the upper dermis, melanophages and pigmentary incontinence. The clinical course can vary. We present here an additional case of LPP-inversus that developed on the both inguinal folds and we review the relevant literature.