ABSTRACT
To estimate whether serum leptin has any effects on body composition during the lactational and postnatal periods, we investigated the relationship of serum leptin levels and anthropometric parameters at right after delivery and 16 weeks after delivery in mothers and their infants. Subjects who signed the concent form, participated in this study were recruited from K university hospital. Characteristics of the subjects ( age; 31.0 +/- 4.2 yr, gestation period; 39.5 +/- 1.0 wk) were investigated and anthropometric parameters ( weight, height, body mass index and percent body fat for mothers, and weight, height, head circumference, chest circumference, and Kaup index for infants) were measured. Serum leptin levels of mothers and their infants also measured. Mean maternal serum leptin levels were 9.9 +/- 8.2 ng/ml and 9.1 +/- 7.2 ng/ml at right after delivery and 16 weeks after delivery, respectively showing no significant differences. Mean infant's serum leptin levels at birth ( 1.8 +/- 0.4 ng/ml) were significantly lower than that of at 16 weeks after birth ( 4.2 +/- 0.8 ng/ml)(p < 0.001) . Leptin levels of male infants were not different from those of female infants. There were no correlations between the maternal serum leptin levels with their body weight, percent body fat after delivery. However, significant correlations were found between maternal serum leptin levels with their body weight, BMI, percent body fat at 16 weeks after delivery ( r = 0.80, p < 0.01; r = 0.90, p < 0.001; r = 0.83, p < 0.01, respectively) . There were no cor-relations between the infant's serum leptin levels and their weight, height, head circumference, and chest circumference. No significant relations were also found between maternal serum leptin levels with those of their infants. As a conclusion, maternal serum levels of leptin should be used with a caution to estimate their infant's leptin levels as well as their anthro-pometric parameters. Further researches are needed to examine the relationship among the leptin levels of mother's serum, breast milk, placenta, and infant's serum.
Subject(s)
Female , Humans , Infant , Male , Pregnancy , Adipose Tissue , Birth Weight , Body Composition , Body Height , Body Mass Index , Body Weight , Head , Leptin , Milk, Human , Mothers , Parturition , Placenta , ThoraxABSTRACT
BACKGROUND: Gastrointestinal bowel movements are reduced by opioid-based anesthesia. Remifentanil is commonly used as total intravenous anesthesia. This study compared to the effect of various anesthetic methods on gastrointestinal bowel movement after colon surgery. METHODS: Ninety patients were allocated randomly into three groups. Thirty patients received intraoperative inhalation anesthesia (desflurane + N2O, Group I), 30 patients received intraoperative total intravenous anesthesia (propofol + remifentanil, Group II), and 30 patients received intraoperative epidural anesthesia (epidural lidocaine + propofol, Group III). All patients received postoperative epidural analgesia with a mixture of ropivacaine and morphine. The time to the first passage of flatus, hospital stay and visual analog pain scale were recorded. RESULTS: There was no significant difference in first passage of flatus among groups (Group I: 92.7 +/- 19.6, Group II: 86.9 +/- 19.4, Group III: 81.9 +/- 12.8 hours, P = 0.063). There were no significant difference in the hospital stay and visual analog scale among the three groups. CONCLUSIONS: Total intravenous anesthesia with remifentanil did not reduce the gastrointestinal bowel movements compared with those of inhalation or epidural anesthesia.
Subject(s)
Humans , Analgesia, Epidural , Anesthesia , Anesthesia, Epidural , Anesthesia, Inhalation , Anesthesia, Intravenous , Colon , Flatulence , Inhalation , Length of Stay , Lidocaine , Morphine , Pain Measurement , Propofol , Visual Analog ScaleABSTRACT
The congenital nasal piriform aperture stenosis (CNPAS) is a rare cause of neonatal airway obstruction and could be easily mistaken as the choanal stenosis or atresia. The piriform aperture is a term used to refer to the anterior nasal openings. The nasal airway obstruction in the neonate can result in respiratory difficulties and may be going to life threatening consequences. Computed tomography demonstrates in detail the underlying anatomic abnormalities which allows differentiation of the CNPAS from other upper airway abnormalities. We reported a case of CNPAS, a 1-month-old male infant presented with respiratory difficulties. Shortly after birth, he had mild respiratory difficulties and there was difficulty passing a nasal catheter intranasally. But he was improved through only conservative management and discharged at the age of 5 days. At the age of 1 month, CT scan revealed bilateral CNPAS.
Subject(s)
Humans , Infant , Infant, Newborn , Male , Airway Obstruction , Catheters , Constriction, Pathologic , Nasal Obstruction , Parturition , Tomography, X-Ray ComputedABSTRACT
Reports of systemic candidiasis in neonates have been noted with major advances in neonatal care permitting the frequent survival of low birth weight infants. We experienced 2 cases of systemic candidiasis associated with skin involvement in very low birth weight infants. One case presented with abdominal distension and an erythematous maculopapular eruption on trunk, buttock, and lower extremities. Culture of peritoneal fluid grew Candida of albicans. In another case, a diffuse erythematous patch was noted on the back and buttock. Culture of blood sample grew Candida of albicans. Despite the treatment with intravenous fluconazole, clinical status of the patients continued to remain unstable, and they died.
Subject(s)
Humans , Infant , Infant, Newborn , Ascitic Fluid , Buttocks , Candida , Candidiasis , Fluconazole , Infant, Low Birth Weight , Infant, Very Low Birth Weight , Lower Extremity , SkinABSTRACT
No abstract available.
ABSTRACT
No abstract available.