A Case of Septo-Optic Dysplasia

Septo-optic dysplasia, named by de Morsier in 1956, includes absence of the septum pellucidum, partial or complete agenesis of the corpus callosum, dysplasia of the anterior third ventricle, and bilateral optic nerve hypoplasia. Associated ophthalmologic disorders are nystagmus, poor vIsion, visualfield defect, astigmatism and optic nerve hyopolasia. The authors experienced a case of septo-optic dysplasia which was confirmed by MRI in 30-year-old male.

A Case of Septo-Optic Dysplasia

Septo-optic dysplasia, named by de Morsier in 1956, includes absence of the septum pellucidum, partial or complete agenesis of the corpus callosum, dysplasia of the anterior third ventricle, and bilateral optic nerve hypoplasia. Associated ophthalmologic disorders are nystagmus, poor vIsion, visualfield defect, astigmatism and optic nerve hyopolasia. The authors experienced a case of septo-optic dysplasia which was confirmed by MRI in 30-year-old male.

Biometric Measurements in Acute Angle Closure Glaucoma

Biometric measurements were made by ultrasonography in 30 eyes of 25 patients (18 Women and 7 men, mean 67.9 yrs) with acute angle closure glaucoma against 52 eyes of 26 age-matched normal persons (20 women and 6 men, mean 65.1 yrs) in order to analyze an affecting factor of lens in acute primary angle closure glaucoma. The 26 eyes of 30 patients' eyes was subjects older than 60 years of age and mean intraocular pressure was 57.06 +/- 16.764 mmHg The mean anterior chamber depth of these patients (1.895 +/- 0.193 mm) was 0.95mm shallower than one of controls (2.840 +/- 0.324 mm). The mean lens thickness was slgmtlCantly larger tor pal1ents (patients 5.024 +/- 0.498 mm, controls 4.168 +/- 0.524 mm, p=0.001). The mean axial length was 0.6 mm shorter for patients (patients 22.385 +/- 0.840 mm, controls 22.985 +/- 0.838 mm, p<0.01). The relative lens position was significantly smaller for patients (patients 0.194, controls 0.214, p=0.0001), but relative posterior capsule position was similar in two groups. The study suggested that the increased thickness and forward positioning of lens was one of important factors for anterior chamber angle closure in primary angle closure glaucoma.

Aging Change of Pupil Size in Normal and Diabetic Patients

It is well recognized that diabetic patients have small pupil. The most likely cause of the abnormally small pupil in diabetics is decreased funcitor of the autonomic nerves. We measured pupil size in 141 control subjects and 53 diabetic patients (29 cases with symptomatic autonomic neuropathy, 24 cases without symptomatic autonomic neuropathy) with portable pupillometry, PUPILSCAN in darkness. Pupils become smaller in healthy and diabetic subjects with advancing age. (log pupil size = 2.05 - 0.066 X age, r: -0.47, p