The Changes of IOP during General Anesthesia

The effects of general anesthesia on intraocular pressure were studied in 30 patients ranging in age from 15 to 48 years old. The intraocular pressure was measured by the Schiotz tonometer. The patients were divided into 2 groups: thiopental-succinylcholine-intubation (Group 1) and thiopental-vecuronium-intubation(Group 2). The results were as follows: 1) IOPs after thiopental(5 mg/kg) administration were decreased significantly compared with the control value in both group(p<0.05). 2) IOP after succinylcholine administration were elevated, but it was not statistically significant compared with the control value. 3) IOP after vecuronium administration was decreased significantly compared with the control value(p<0.05). 4) IOP after intubation were elevated significantly compared with control value in both groups(p<0.05). 5) IOP at 10 minutes after the induction of general anesthesia was not changed compared with the control value in group 1, but was decreased significantly in group 2(p<0.05).

An Electron Microscopic Study of Corneal Blood Staining After Hyphema

The authors experienced corneal blood staining after traumatic hyphema with primary open angle glaucoma and studied corneal blood staining by electron microscope. The electron microscpic finding were as follows: 1. The destructive RBC particles were found in entire cornea except deep stroma by light microscope. 2. The destruction of endothelium and intact Descemet's membrane were found and few RBC particles in the keratocyte and interlamellar space were observed by electron microscope. 3. Amorphous granules in the superficial stroma were darker than the ones in the deep stroma by electron microscope. 4. The granules were observed between basal cell layer and wing cell layer in epithelium. We suggest that clearing mechanism of corneal blood staining are scavening action of phagocytic cells and migration from deep layer to superficial layer of granules.

The Effects of Several Anesthetics on Intraocular Pressure / 대한마취과학회지

The effects of several anesthetios (thiopental, ketamine, Innoyar) and muscle relaxants (succinylcholine and vecuronium) on IOP, blood pressures and pulse rates were studied in 60 Patients ranging in are 12 to 56 years. IOP was measured with the Schiotz tonometer. In addition to tonometric determinations, the blood pressures and pulse rates were recorded. The patients were divided into 4 groups: Thiopental-succinylcholine-intubation(Group 1) ; Ketamine-succinrlcholine-intubation (Group 2) ; Innovar-succitrlcholine-intubation (Group 3) and Thiopental-vecuronium-intubation (Group 4) . The results were as follows : 1) In group 1 and 4, IOP changes following thiopental(5 mg/kg) administration showed highly significant decreases(p0.05) and in group 2, IOP changes after 5 minute following succinylcholine administration shewed highly significant increases (p<0.01) . 3) In group 3, IOP changes after 5 minutes following Innovar (1 ml/15 kg) administration showed highly significant decreases (p<0.01) compared with the control value. 4) IOP changes after 1 minute of endotracheal intubation showed highly significant inc- reases (p<0.01) in all groups compared with the control value. 7) In group 4, IOP changes following vecuronium administration instead of succinylcholine showed highly significant decreases, but could not prevent the increases in IOP following endotracheal intubation. 6) In all groups, blood pressures and pulse rates showed highly significant increases after endotracheal intubation. 7) After succinylcholine administration, blood pressures showed aignificant increases in group 1 and highly significant increases in group 2. 8) In group 2, blood pressures showed highly significant increases after ketamine administration.

A Case of Metastatic Conjunctival Tumor

The incidence of metastasis to the eye and its related structure on recent studies appear to be more common than previous studies demonstrate. The authors experienced a case of hepatocellular carcinoma metastatic to the conjunctiva. A 48-year-old man with known hepatocellular carcinoma in the liver had a mass surrounded with blood clot on the upper palpebral conjunctiva of right eye. A biopsy demonstrated that the lesion was hepatocellular carcinoma metastatic to the conjunctiva.