A Case of Kyrle's Disease / 대한피부과학회지

We report a case of Kyrle's iisease occurring in a 60-year-old woman with chronic renal failure. The patient had multiple hyperkeratotic papules with a central plug on the back, and in the upper and lower extremities. Histopathological findings showed epidermal invagination filled with parakeratotic column and basophilic debris. Many dyskeratotic and vacuolated cells were present below the keratotic plug, and penetration of the parakeratotic column into the dermis was seen.

Patch test and Specific IgE Concentration with House Dust Mite Antigens in Atopic Dermatitis Patients / 대한피부과학회지

BACKGROUND: Recently several papers have been published dealing with positive patch reactions to house dust mite antigens in atopic dermatitis patients. The possibility that house dust mite antigens, brought in direct contact with the skin such as through the air, may contribute in the pathogenesis of the dermatitis, is an interesting aspect of the relationship between atopic dermatitis and allergic reactions. OBJECTIVE: The purpose of this study is to evaluate type-IV and type-I hypersensitivity to house dust mite antigens in atopic dermatitis patients. METHODS: We performed the patch test and chemiluminescent assay(CLA) for house dust mite antigens in 42 patients with atopic dermatitis and 10 normal controls. RESULTS: 1. Positive reactions of the patch test in patients with atopic dermatitis were 11(26.2% ) for the Df antigen and 10(23.8%) for the Dp antigen. 2. Positive reactions of CLA in 42 patients with atopic dermatitis were 12(28.5%) for both Df and Dp antigen, but only one(10%) for both Df and Dp antigen in 10 normal controls. 3. A highly significant correlation to house dust mite antigens existed between the patch test and CLA, but some patients showed a positive reaction in the patch test despite the level of IgE which was in class 1 or 0. 4. There was no significant statistical correlation between the severity of atopic dermatitis and the positive reaction rate of both the patch test and CLA CONCLUSION: These results suggested that in atopic dermatitis patients with positive patch test reactions to house dust mite antigens, delayed type hypersensitivity reactions to these antigens might play an important role in the development of atopic dermatitis skin lesion .

Two Cases of Vulvar Syringoma / 대한피부과학회지

We report two cases of vulvar syringorna in a 40-year-old women and a 28-year-old woman who had 2-3mm sized, brownish papules on both valvar areas an l-3rnm sized, yellow-brownish papules on both vulvar ares with yellowish milia-like lesion the surface, respectively. Microscopically the lesions revealed characteristic findings of syrinzoiza However the second case showed a small cystic duct in the papillary dermis, which is lineilly a stratified epithelium and filled with concenteric lamellae of keratin.

Comparative study on the morphology of renal pelvoclyceal systems of healthy persons and urinary stone formers by excretory urography / 대한비뇨기과학회지

Until recently almost exclusively clinicochemical urine parameters have been used to determine the risk of urinary stone formation, because the urinary stone disease is considered as one of metabolic disorders. But the morpholgy of renal pelvocalyceal system also affects on the formation of stone particle and its growth, mainly by establishing urinary stasis. We reviewed 163 excretory urograms retrospectively, and pelvocalyceal systems of healthy persons and urinary stone formers were compared with regard to their morphology. In summary of the study, the majority of pelvocalyceal systems of urinary stone formers showed (1) an increased number of papillae; (2) a greater cranial and caudal exlension of pelvocalyceal sysrem:(3) an increased circular radius of the pelvocalyceal system and hence an increased pelvocalyceal system volume ;(4) an increased pelvic area, especially an enlarged total calyx area and hence a larger total area. (5) a higher degree of ramification and a higher number of branches in the calyx groups ; (6) a more sharp angle between the most caudally situated calyx neck and the direction of pelvic outlet :(7) a highly situated origin or the ureter more frequently ;(8) more frequent ampullary patterns of pelvocalyceal system. But the number of major calyx, the total calyx angle and the angle between the direction of pelvic outlet and the main direction of the ureter showed no statistically significant difference between the urinary stone formers and the healthy persons. The results indicate that the study on the morphology of the renal pelvocalyceal system by excretory urography may be used as a screening test to determine the risk of urinary stone formation.

A study on the comparision of various imaging methods for the staging of renal cell carcinoma / 대한비뇨기과학회지

The diagnostic significance of ultrasonography, computed tomography and magnetic resonance imaging for predicting the stage of tumors was evaluated by comparing their results with preoperative and histopathologic findings. The 24 patients who were diagnosed as renal cell carcinoma by histopathologic finding have taken preoperative examination such as ultrasonography, computed tomography. Additionally, magnetic resonance imaging was performed in 15 patients among them. The T stage was determined correctly by magnetic resonance imaging in 87% of the cases, by computed tomography in 80%. We suggested that a computed tomography is reliable imaging method for evaluating the T,N category preoperatively, but magnetic resonance imaging is more sensitive than a computed tomography in predicting the stage of renal cell carcinoma and a magnetic resonance imaging can replace the computed tomography.

A case of malignant melanoma of the urinary badder / 대한비뇨기과학회지

Malignant melanoma of the urinary bladder is very rare, 7 cases were reported in the literature. The tumor shows early metastasis with poor prognosis. Treatment measures include surgical extirpation, radiotherapy and chemotherapy but the results were bad.Herein, we report a case of malignant melanoma of the urinary bladder in a 45-year-old man which was managed by transurethral resection and combination chemotherapy.