ABSTRACT
BACKGROUND: Migraine can cause suffering and reduce functioning and productivity. Migraine is usually suboptimally treated, with many migraineurs not being satisfied with the applied acute treatment. Migraine-ACT is a four-item assessment tool used by clinicians to identify patients who require a change in their acute treatment. The objective of this study was to determine validity and reliability of the Korean Migraine-ACT. METHODS: Participants who visited Hallym University Sacred Heart Hospital neurology clinic for headache were recruited. The survey employed SF-36, HIT-6, and Migraine-ACT. Headache diagnosis was assigned on ICHD-II after completing a semistructured diagnostic interview. RESULTS: A total of 52 migraine patients aged 38.7+/-14.7 years (mean+/-SD) were recruited. There was a positive correlation between general summary scores on SF-36 and Migraine-ACT (Spearman's correlation coefficient=0.39, p<0.05) and a negative correlation between HIT-6 scores and Migraine-ACT scores (Spearman's correlation coefficient=.0.52, p<0.05). Cronbach's alpha of Migraine-ACT was 0.78. CONCLUSIONS: These results indicate that Korean Migraine-ACT is a valid and reliable instrument to identify migraine patients who require a change in their acute treatment.
Subject(s)
Aged , Humans , Efficiency , Headache , Heart , Migraine Disorders , Neurology , Reproducibility of Results , Stress, PsychologicalABSTRACT
BACKGROUND: Quality-of-life measurement represents an important tool for evaluating the management and impact of headache on individuals and society. The Headache Impact Test-6 (HIT-6) is a simple instrument developed to assess headache-related disability in Western countries. The objective of this study was to determine the reliability and validity of the Korean HIT-6. METHODS: Participants were recruited from patients who visited the Neurology Clinic of Hallym University Sacred Heart Hospital due to headache. The survey included the SF-36 and HIT-6. Headache diagnosis was assigned using ICHD-II after completing a semistructured diagnostic interview. RESULTS: A total of 43 patients were recruited, who were aged 35.2+/-13.6 years (mean+/-SD). Thirty-three and three were diagnosed as having migraine and probable migraine, respectively. Eight and two were diagnosed with tension-type and probable tension-type headache, respectively. There was a negative correlation between the total SF-36 and HIT-6 scores (Spearman's correlation coefficient=-0.64, p<0.01). Similar significant negative correlations were also observed between SF-36 physical health summary and HIT-6 scores (Spearman's correlation coefficient=-0.54, p<0.01), and between SF-36 mental summary and HIT-6 scores (Spearman's correlation coefficient=-0.60, p<0.01). The Cronbach's alpha of HIT-6 was 0.85. CONCLUSIONS: The Korean HIT-6 is a valid and reliable instrument for assessing headache-related quality of life.
Subject(s)
Aged , Humans , Headache , Heart , Migraine Disorders , Neurology , Quality of Life , Reproducibility of Results , Tension-Type HeadacheABSTRACT
Myoclonus manifests in a variety of situations including epilepsy, metabolic derangements, brain lesions, and toxicity of drugs. A 57-year-old woman with end-stage renal disease was given gabapentin 900 mg/day for legs' paresthesia. Two days after taking gabapentin, multifocal myoclonus developed involving all extremities. Three days after discontinuation of gabapentin, myoclonus resolved completely. No deterioration of renal function was noted before and after the occurrence of myoclonus. Administration of gabapentin should be performed with caution in patients with impaired renal function.