Cerebral chromoblastomicosis--a rare case report of cerebral abscess and brief review of literature--a case report.

A rare case of Cerebral Chromomycosis caused by chromogenic fungus Cladosporium trichoides in a 35 year old male with classical presentation of cerebral abscess is being presented. The case report lays emphasis on the histological diagnosis of chromogenic fungus in the wall of the abscess cavity, surgically removed from a well delineated circumscribed lesion in the frontal lobe of the cerebrum. The causative fungus could be detected even in unstained paraffin sections. The diagnosis could be made only after surgical removal and histopathological examination. The mycological culture could not be made as the material was received in formaldehyde fixative. The unique features of the case is its recurrence free uneventful survival five years after surgical excision. This is probably the fifth reported case of cerebral chromomycosis from India and first of its type from arid zone of Rajasthan.

Seroprevalence of toxoplasmosis in Jodhpur, India.

Toxoplasma gondii specific IgG and IgM antibody levels were determined in sera of 135 healthy human volunteers comprising of students (85), staff (50) and 115 patients comprising of 65 adults and 50 children whose blood was taken for some other investigations. None of the subjects had congenital disease or any other sign or symptom suggestive of Toxoplasmosis. None of the women had had obstetric history or gave birth to infants with congenital defects. Toxoplasma gondii specific IgG and IgM antibodies were assayed by ELISA. Sero positivity to one or both classes of antibodies was observed in 17.2%. However, active infection i.e. IgM positive or high (> 210 Eu/ml) level, IgG was observed only in 4.4%. Antibody levels and seropositivity rate increased with age. No statistically significant differences in the levels of antibodies were observed in relation to sex, socioeconomic status, place of living (rural/urban) and dietary habit (vegetarian/non vegetarian). However, relatively higher prevalence of seropositivity was observed in males and villagers.