ABSTRACT
Calcinosis cutis is the deposition of insoluble calcium salts in the skin. Dystrophic calcinosis cutis is diagnosed when calcium is deposited in the previous damaged tissue and the values of calcium and phosphorus levels are normal. We report a case of dystrophic calcinosis cutis in a 32-year-old man. He had experienced a burn accidentally on the left anterior thigh at 2 years old. About 1 year ago, an ulcer developed on the burn scar. He found the chalky material in an ulcer and removed it, then the ulcer healed. But, new ulcers developed in a linear pattern. Histopathologically, amorphous eosinophilic materials that were black with Von Kossa stain were deposited in the dermis.
Subject(s)
Adult , Child, Preschool , Humans , Burns , Calcinosis , Calcium , Cicatrix , Dermis , Eosinophils , Phosphorus , Salts , Skin , Thigh , UlcerABSTRACT
Blastomycosis-like pyoderma is an uncommon vegetating tissue reaction, often secondary to a bacterial infection occurring in patients with a compromised immune system. We describe a clinically blastomycosis-like pyoderma on the right ankle and knee in a patient with iatrogenic Cushing syndrome, hypertension, hypercholesterolemia and congestive heart failure.
Subject(s)
Humans , Ankle , Bacterial Infections , Cushing Syndrome , Heart Failure , Hypercholesterolemia , Hypertension , Immune System , Knee , PyodermaABSTRACT
Dermatomyositis is a rare inflammatory myopathy with characteristic skin manifestations and muscular weakness. Vesicle or bulla formation in the dermatomyositis is rare and probably related to the presence of an internal malignant process. We report a case of dermatomyositis associated with esophageal cancer in a 72-year old man who had vesicles and bullae on his arms. He had erythema and edema on the face, chest, abdomen, back and legs for 20 days. Tense vesicles and bullae were found on his forearms and hands. Diagnosis of dermatomyositis was established by clinical manifestations, muscle enzyme study, electromyogram and histopathological findings of the skin. Adenocarcinoma of esophagus was found by gastroendoscopy. He was treated with total esophagectomy and topical steroid, but died of pneumonia and septicemia.
Subject(s)
Aged , Humans , Abdomen , Adenocarcinoma , Arm , Blister , Dermatomyositis , Diagnosis , Edema , Erythema , Esophageal Neoplasms , Esophagectomy , Esophagus , Forearm , Hand , Leg , Muscle Weakness , Myositis , Pneumonia , Sepsis , Skin , Skin Manifestations , Thorax , Transcutaneous Electric Nerve StimulationABSTRACT
No Abstract Available.
ABSTRACT
Down syndrome is associated with a large number of abnormal skin features including syringoma. Milia-like idiopathic calcinosis cutis is one of the rare dermatoses associated with Down syndrome. It has been reported in children with Down syndrome and clinically suggested as milia. The histological features show small nodular foci of calcium within the papillary dermis and transepidermal elimination of calcium deposits occasionally. We describe a 14-year-old female affected by Down syndrome, who had whitish papules on both the dorsal hands and feet and periorbital syringomas. Histopathological findings of the papule on the dorsal hand showed calcium deposits as amorphous, basophilic masses in the upper dermis and focal discharge of calcium by means of transepidermal elimination.
Subject(s)
Adolescent , Child , Female , Humans , Basophils , Calcinosis , Calcium , Dermis , Down Syndrome , Foot , Hand , Skin , Skin Diseases , SyringomaABSTRACT
Malignant eccrine poroma, or eccrine porocarcinoma, is a rare malignant cutaneous appendageal tumor arising from the intraepidermal eccrine sweat duct(acrosyringium), and usually develops ia an eccrine poroma of long-standing. We report a case of malignant eccrine poroma on the left buttock in a 72 year-old female. She was presented with a slightly pruritic, well-defined, reddish, firm, 4.5 x 4.5 x 0.7cm sized, protruding, ulcerated tumor. Histopathological examination revealed well-defined tumor cell nests in the epidermis and dermis. The tumor nests consisted of areas of eccrine poroma cells with benign appearance adjoining areas of anaplastic cells. Duct-like structures were observed within the tumor nests and showed a PAS-positive, diastase-resistant reaction. On immunohistochemical staining, the tumor cells were, positive for EMA, and most of tumor cells were negative but the duct-like structures were positive for CEA. She was treated with surgical excision. During the three year follow up period after excision, there was no recurrence.