ABSTRACT
@#Zinc deficiency is a major public health problem in some resource-limited countries. This study assesses the zinc status of 90 pre-school-age children, aged 12 to 59 months, resident in the National Capital District (NCD), Papua New Guinea. Children attending the Children's Outpatient Clinic at Port Moresby General Hospital participated in this cross-sectional study. Informed consent was obtained from parents before using blood samples from their children. Flame atomic absorption spectrometry was used to measure the serum zinc concentration. C-reactive protein (CRP) in serum was measured by enzyme immunoassay and used to interpret the serum zinc data. The median serum zinc concentration for all the children was 83.6 μg/dl and the interquartile range was 64.6-103.7 μg/dl. The prevalence of serum zinc deficiency (Zn <65.0 μg/dl) among all the children was 26%; and 42% had elevated serum CRP level. Serum zinc deficiency was present among 31% and 20% of the children in the 12 to 24 months and over 24 months age groups respectively. The prevalence of serum zinc deficiency among the male and female children was 28% and 25% respectively. The high prevalence of zinc deficiency among the children may be caused by the high rate of subclinical infection and low bioavailability of absorbable zinc in the popular foodstuffs that they are consuming. The prevalence of zinc deficiency among the children with and without elevated serum CRP strongly suggests the need for continuous monitoring of the zinc status of pre-school-age children in the NCD