ABSTRACT
As of Apr. 22, 2020, the World Health Organization (2020) has reported over 2.4 million confirmed coronavirus disease 2019 (COVID-19) patients and 169 151 deaths. Recent articles have uncovered genomic characteristics and clinical features of COVID-19 (Chan et al., 2020; Chang et al., 2020; Guan et al., 2020; Zhu et al., 2020), while our understanding of COVID-19 is still limited. As suggested by guidelines promoted by the General Office of National Health Commission of the People's Republic of China (2020) (from Versions 1 to 6), discharged standards for COVID-19 were still dependent on viral real-time polymerase chain reaction (RT-PCR) tests of respiratory specimens, showing that recovered COVID-19 patients with twice negative RT-PCR could meet discharge criteria. Here, we examined two cases in which nucleic acid test results were inconsistent with clinical and radiological findings, leading to suboptimal care.
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Betacoronavirus , China , Clinical Laboratory Techniques , Coronavirus Infections , Diagnosis , Pandemics , Patient Discharge , Pneumonia, Viral , Diagnosis , Real-Time Polymerase Chain Reaction , Reverse Transcriptase Polymerase Chain Reaction , Sputum , VirologyABSTRACT
The original version of this article unfortunatelycontained a mistake. For Fig. 1a in p.409, the citationof a reference, as well as the permission to reprint thispicture, was missing. The correct version and thecorresponding reference are given below: (a) Chest computed tomography (CT) image of Patient 1 onadmission presents multiple ground-glass opacities distributedin the periphery of inferior lobe of both lungs. Reprinted fromZhang et al. (2020), with kind permission from SpringerNature.