1.
Chinese Journal of Hypertension
;
(12): 152-153, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-411155
ABSTRACT
Objective To investigate the effect of cilazapril on reactivit y of blood vessels in diabetic rats. Methods The mesenteric vessels of streptozotocin induced diabetic rats wer e perfused with Kreb-Ringer's solution in vitro,the mesenteric vessels reactivi ty of diabetic rats was measured by physiological recorder. Results The responsive continual time to norepinephrine was delay ed signific antly(9.4±3.1 vs 5.2±2.1,P<0.01) and the highest perfusion pressu re decrease significantly in diabetic rats(5.12±0.87 vs 7.81±0.92 kPa, P<0.01); When taken cilazapril showed no difference in these indexes in diabetic animal s.