ABSTRACT
Twelve male patients with gout in the remission stage were administered Boiogi-to extract (5.0g/day), Mokutsu (Akebia quinata) extract (0.5g/day) and Shazenshi (Plantago asiatica) extract (0.5g/day) twice a day, The efficacy of this combination was then evaluated. (Prior to commencement of this study, all patients carried both diet and exercise therapies and contniued them during this study).<br>After the 12-week administration period was completed, significant results were observed. Notably, there was a decrease of body weight, decrease in serum uric acid and serum glycerol, and an increase in serum HDL-cholesterol. By the 24th week after therapy commencement, the body weight did not increase and the serum uric acid did not elevate. No side effects and no gout attacks ware reported. The clinical symptoms of fatigue, hidrosis, oliguria, and edema also improved. In conclusion, this kampo formula was considered to be effective in the treatment of gout.