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Background: Acute Kidney Injury is a common condition in critically ill children, and it is independently associated with increased mortality. Etiology of AKI in admitted patients is multi factorial. The present study was conducted to determine possible etiologies and to know short term outcome.Methods: A prospective case series study was conducted in our PICU from Nov 2014 to October 2015. The cases fulfilling criteria as AKI, as per definition were included in study. The urine output was monitored, base line blood urea and serum creatinine was estimated at admission and on alternate days till recovery. Investigations were done to know exact etiology of prerenal, renal or post renal AKI. Cases were managed accordingly and short term outcome was noted.Results: Out of 150 cases studied, 87(58%) were boys and 63(42%) were girls.' Ninety three cases (62%) had oliguria and remaining patients had non-oliguric AKI. Majority of cases in the study belonged to prerenal AKI, followed by renal and post renal AKI. Amongst 150 cases,136 children managed conservatively,11 cases required hemodialysis and 3 cases peritoneal dialysis. In our study, 16 cases succumbed with mortality of 10.66%.Conclusion: AKI is common associated condition in children admitted to PICU. AKI is commonly seen with acute gastroenteritis with severe dehydration, sepsis, glomerulonephritis and dengue shock syndrome. Most of these conditions are easily preventable. Early and effective management of hypovolemic shock and sepsis is also crucial in prevention of AKI.
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Background: Scorpion stings are common in India. Presentation of scorpion sting may vary from localised pain at the site of the sting to life threatening condition. Systemic envenomation will even result in death among one third of the subjects. The present study was conducted to determine the clinical presentation, course, complications and outcomes of scorpion sting envenomation among children as they are sensitive to scorpion envenomation.Methods: 50 cases of scorpion sting, admitted to 2 hospitals, under JJMMC, Davangere for 1 year were included. A detailed clinical history followed by examination was done. Relevant investigations were also done. All the cases were monitored for complications and managed accordingly.Results: Maximum number of cases were noted in the age group of 1-3 years and 10-12 years. 58% of them were boys, 54% of the cases had red scorpion sting. Pain at the sting site, diaphoresis and restlessness were the most common presenting symptoms. The common signs noted were restlessness, cold extremities and tachycardia. Commonest complications were peripheral circulatory failure, pulmonary oedema, myocarditis and congestive cardiac failure. Majority of cases recovered without any sequelae.Conclusions: Present study we conclude that majority of the cases were among boys belonged to 1-3year age group. Red scorpion sting was common, and commonest presentation was pain and recovered without any sequelae.
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Background: Placenta plays a major role in growth and development of the fetus as it helps in both exchange of nutrients and removal of waste. Even though it yields a valuable information of prognostic significance for the newborn, majority of the time it will be discarded after the gross examination. Hence the present study was conducted to determine the placental pathology and its correlation with fetal outcome.Methods: The present study was carried out in Davangere for a period of 2 years. The placenta of 100 parturients, more than 28 weeks of gestation were included for the present study. The data was collected after detailed review of the obstetric case records. Placentas were examined soon after delivery. After the gross examination was complete, the placentas were put in a labelled plastic container. The placentas were re-examined macroscopically again by the pathologist. Cut-section examination was done. Then, at least 4 appropriate blocks were taken for each placenta. They were stained with hematoxylin-eosin stain and examined under the microscope. The histopathological examination was conducted as per proforma.Results: One hundred placentae belonging to one hundred babies were studied among which 80% of the maternal cases had anaemia, 68% were term infant, 37% had IUGR. Eccentric insertion of the cord was observed to be the commonest (51). Marginally inserted membranes were seen most frequently (97).Conclusions: In the present study we conclude that placental reserve is large and small alteration do not affect the pregnancy outcome. The placental changes are not specific to a particular condition affecting the pregnancy.
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Background: In neuropsychological assessment, the time taken by a subject or patient to respond tostimulus provides valuable information about processing in central and peripheral nervous system. Reactiontime is a simple and inexpensive method commonly used in cognitive and sport physiology to assess thesensory-motor performance of an individual.Objective: To compare and validate the baseline values of simple reaction time obtained using the PC 1000Hz reaction timer with Biopac® MP 36.Materials and Methods: 50 healthy subjects (32 males and 18 females) with age of 22.78±3.90 yrs andBMI of 24.820±3.59 kg/m2 participated. Visual (VRT) and auditory (ART) reaction time were estimated usingPC 1000 Hz reaction timer and Biopac® MP 36 separately for minimum of three trials each.Results: There was no significant difference found in ART and VRT values of the subjects estimated by PC1000 Hz and Biopac® MP 36. A strong significant (P<0.01) correlation was found in ART (r=0.92) and VRT(r=0.94) in between the devices. Bland Altman plot also showed that variations for VRT and ART were withinthe acceptable range.Conclusion: The present validation study recommend that the assessment of simple reaction time forauditory and visual stimulus by PC 1000 Hz reaction timer is reliable one and compared with other techniquesit has more advantages such as portable in nature and simplicity to use either in laboratory or in fieldoriented study for the evaluation of psychomotor and cognitive function.
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Background: Surgeries are associated with significant postoperative pain. Postoperative pain is usually of longer duration and recurs after few hours. The caudal epidural block is considered as the procedure of choice for pain relief in such cases. The purpose of this study is to evaluate the postoperative analgesic efficacy of epidurally administered Bupivacaine and Tramadol in surgeries including cesarean sections and other gynecological surgeries. Aim of the Study: Effectiveness of bupivacaine and tramadol in postoperative pain management Materials and methods: A total of 100 cases were included in this study between the age group of 15 years and 65 years. They were grouped into group A - Bupivacaine group and group B - Tramadol group. Results: The mean interval between 1st and 2nd dose in Group A was 268.15 minutes and in Group B was 398.35 minutes. Dose intervals between 2nd and 3rd dose in Group A were 279.52 minutes and in Group B 371.41 minutes. Dose intervals between 3rd and 4th dose in Group A were 266.42 and in Group B was 321.15 minutes. There were no cases which required the 4th dose of the drug in this study. Conclusion: Postoperative consumption of analgesia was higher in the Bupivacaine group. Epidural tramadol 100 mg in 10 ml provides better and longer duration of anesthesia with rapid onset and no incidence of complications.
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This Study evaluated the effect of disinfection methods on the Flexural Properties of Auto Polymerizing Resin. (Tooth Colored and Repair Resin). Specimens were exposed to microwaves for 15 min and 2 % Glutaraldehyde for 10 hours. Specimens stored in Water for 12 hours were used as control. For each procedure 10 specimens were used. The result indicated that changes in Flexural Strength observed were of no significance for both Tooth Colored and Repair Resin. The Microwave method is useful alternative to immersion disinfection having advantage of less time consumption.