ABSTRACT
To evaluate the results of Verteporfin photodynamic therapy [PDT] in vasoproliferative tumors [VPT] of the retina and retinal capillary hemangiomas [RCH]. In a retrospective case series, 6 tumors in 5 eyes with VPT, and 3 RCH in 3 eyes underwent PDT which was performed using intravenous Verteporfin. Eyes were evaluated for tumor regression, final bestcorrected visual acuity [BCVA], and final retinal status. Patients were followed for a mean period of 7.1 +/- 3.9 months. Mean number of PDT sessions for each tumor was 1.33 [range 1-2]. Overall, mean BCVA improved from 1.7 +/- 1.06 to 0.88 +/- 0.8 logMAR [P=0.017]. Tumor thickness decreased from 3.53 +/- 0.83 to 1.73 +/- 0.73 mm [P<0.001]. Subgroup analysis revealed improvement in BCVA and tumor thickness in the VPT group [P=0.04]. However, in the RCH group, there was no statistically significant improvement in BCVA [P=0.43] despite significant reduction in tumor thickness [P=0.024]. A favorable outcome characterized by improved or unchanged visual acuity was achieved and the tumor regressed in all eyes. Subretinal fluid was absorbed in all eyes except for one eye with preoperative proliferative vitreoretinopathy. Vasoproliferative tumors and retinal capillary hemangiomas can be treated effectively by Verteporfin PDT and a favorable outcome can be expected
ABSTRACT
To evaluate the outcomes of vitrectomy for complications of branch retinal vein occlusion [BRVO]. This retrospective study, included patients who underwent vitrectomy surgery due to the complications of BRVO over an 11-year period. Visual acuity and retinal condition were evaluated before and after surgery. The study included 30 eyes of 30 patients with mean age of 64.7 +/- 10.92 [range 41-85] years. Vitrectomy was performed for vitreous hemorrhage in 23 eyes [76.6%], for tractional macular detachment in 5 eyes [16.6%] and for combined tractional macular detachment and vitreous hemorrhage in 2 eyes [6.6%].The patients were followed for a mean of 15.43 +/- 12.5 months [range 6-60 months]. Visual acuity improved from 2.6 +/- 0.66 to 0.92 +/- 0.75 LogMAR after operation [P<0.001]. Visual improvement was significant in vitreous hemorrhage group [P<0.001], however, it was not significant in the other two groups [both Ps= 0.1]. Visual acuity remained unchanged in 2 patients and decreased in two other patients. The most common cause of vitrectomy for complications of BRVO was vitreous hemorrhage. Patients with tractional macular detachment with or without vitreous hemorrhage had less improvement in visual acuity in comparison to patients with vitreous hemorrhage alone