ABSTRACT
The purpose of this study was to evaluate the predictability, efficacy, and safety of LASIK in the management of both undercorrection and overcorrection following RK. This prospective study included 30 eyes of 18 patients. All patients underwent previous RK surgery to treat myopia and all of them had residual refractive defect after surgery. Patients were divided according to this residual refractive defect into two groups: Group 1 [undercorrection group] included 17 eyes and group 2 [overcorrection group] included 13 eyes. All eyes underwent LASIK to correct the residual defect. The mean interval between RK and LASIK was 26 +/- 9.1 months [range 12-60 months]. All the patients were followed up for at least six months postoperatively. At the end of the 6-month follow-up period, in group 1, 14 eyes [82%] were within the +/- ID zone of intended correction, 13 eyes [76%] had UCVA of more than 0.5, and 16 eyes [94%] showed improvement or no change in BCVA. In group 2, 10 eyes [77%] were within the +/- ID zone of intended correction, 9 eyes [69%] had UCVA of more than 0.5 and 12 eyes [93%] showed improvement or no change in BCVA. Laser in situ keratomileusis performed to treat undercorrection and overcorrection after RK was predictable, effective and safe. However, special precautions should be taken pre- and intraoperatively to ensure its safety
Subject(s)
Humans , Male , Female , Keratomileusis, Laser In Situ , Follow-Up Studies , Treatment Outcome , Prospective StudiesABSTRACT
Several techniques are used to reposit dislocated intraocular lenses [IOLs]. In cases of a dislocated capsular bag containing the IOL, a dislocated IOL with a large haptic, or a miotic pupil, it is not easy to see the haptic ends to place the suture loop. A scleral fixation technique that creates 2 corneal tunnels was used. A double armed 10-0 polypropylene suture loop can be introduced through 1 corneal tunnel and placed around any accessible part of the haptic with the help of a bent 26 gauge needle. This step can be repeated through the second corneal tunnel to catch the other haptic, if it is displaced
Subject(s)
Humans , Male , Female , Lens Subluxation/surgery , Scleral Buckling , ScleraABSTRACT
Objective: We aimed to evaluate dyspeptic hemodialysed patients regarding upper endoscopy findings and HP status. Also to determine the accuracy of several tests, including culture, histology, rapid urease test, serology and Hp stool antigen to screen for H. pylori infection in dyspeptic hemodialysed patients and evaluate the success of eradication therapy in patients with ESRD
Patients and methods: 44 patients with ESRD on regular hemodialysis and 40 dyspeptic patients with normal renal function as a control group were included in the study. All patients underwent upper endoscopy with biopsy intake for HP histopathology, culture and rapid urease test [RUT]. HP positive result was based on histopathology and or culture. HpSA, and Hp-lgG were also performed. HP infected patients were scheduled to undergo 7-day triple therapy and the success of eradication therapy was investigated
Results: 20 of ESRD patients [54.5%] and 25 patients of control group [62.5%] were proven to be infected with HP. The endoscopy findings of the gastroduodenal mucosa in dialysis patients were similar to that of controls, as was the incidence of peptic ulcers. Dialysis patients had a significantly lower prevalence of H. pylori infection than control subjects. In the histological study. H. pylori-positive patients had significantly higher inflammation and activity scores than H. pylori-negative patients for both dialysis patients and controls. The culture technique provided sensitivity, specificity, PPV and NPV of 54.9, 100, 100 and 70.6%, respectively. The CLO test provided sensitivity, specificity, PPV and NPV of 98, 90.0, 92.1 and 98.9%, respectively. The histology provided sensitivity, specificity, PPV and NPV of 93.4, 90.6, 90.5 and 94.0 %, respectively. The serological test of IgG antibodies yielded sensitivity, specificity, PPV and NPV of 96.0, 64.0, 78.6 and 95.9%, respectively. For the detection of HPSA using FemtoLAB yielded sensitivity, specificity, PPV and NPV of 86.0 100, 100, and 91.0%, respectively, using Premier Platinum yielded sensitivity, specificity, PPV and NPV of 58.0, 86.0 92.0 and 53.0%, respectively, simple rapid test yielded sensitivity. specificity. PPV and NPV of 61.0% 78%, 74.0% and 67% respectively
Conclusion: Upper GI abnormalities are common among HD patients. Biopsy proven antral gastritis is the most common histological diagnosis among these patients and is highly associated with H. pylori infection. Prevalence of H.pylori infection in HD patients is similar to those with normal renal function undergoing endoscopy for dyspepsia. FemtoLAB HpSA is a noninvasive reliable. inexpensive, and reproducible test for diagnosis and follow up of eradication of HP infection in ESRD patients on regular hemodialysis. Detection and treatment of HP improved dyspeptic symptoms in ESRD patients on hemodialysis
ABSTRACT
Background: The frequent and periodic evaluation of crohn's disease [CD] activity is vital in planning the proper therapy, surgical or pharmacological, monitoring drug effects and detecting post-operative recurrence. The evaluation of inflammation is currently based on a combination of clinical symptoms, physical findings, laboratory parameters, endoscopy and various radiology studies. So far, an absolute reference method to assess disease activity doesn't exist, and many parameters are used by the physicians
Objective: We investigated magnetic resonance imaging [MRI] as a tool to evaluate CD activity in newly diagnosed and follow up patients in correlation with clinical and laboratory markers represented by crohn's Disease Activity lndex [CDAI]
Patients and Methods: This study included 27 patients with proven CD. Twelve patients were included in their 1st month from initial diagnosis. Fifteen patients were regular follow up. Patient evaluation included: careful clinical evaluation, laboratory tests, colon ileoscopy, and if needed barium studies. MRI evaluation was performed at the level of the pathological bowel-loops for the following parameters: bowel-wall thickness [WT]; wall enhancement [WE]; and wall signal on T2- W [SPIR] images
Results: Clinically active disease with CDAI score above 150 was noted in fifteen patients. All 27 patients had ileal CD. Ten patients had ileocolonic CD. One patient had gastric in addition to her ileocolonic disease. Magnetic resonance imaging [MRI] findings were: WT was normal in all patients with inactive disease, while in patients with active disease WT was mild in 2 patients, moderate in 4 patients, and severe in 9 patients. WE was normal in 10 patients, and mild in 2 patients of the inactive disease patients, while mild in 8 patients, and severe in 7 patients of the active disease patients. In inactive disease patients T2Wsignal was mild in 1 patient, and absent in 11 patients, while it was high in 7 patients, and mild in 8 patients of the active disease patients. Statistically significant correlation was noted between WT and CDAI, WE and CDAI, and T2W and CDAI. Also, significant correlation was noted between WT and WE, and T2W and WE
Conclusion: MRI can play a larger role in the clinical assessment of CD activity. MRI has shown good accuracy in detecting the inflammatory changes of CD and in differentiating non-active form active disease