ABSTRACT
Medical plants entail numerous therapeutic capabilities due to their antimicrobial activities. During the present study, the antimicrobial activity of aqueous and methanol extracts of Heracoleum Persicum was determined in vitro. We have gathered the aforementioned plant from heights of Ashkour near Tonkabon. The antimicrobial activity of aqueous and methanol extracts was determined against 14 bacterial and 2 fungal specimens according to the disc diffusion, MIC [minimal inhibitory concentration], and MBC [maximum bactericidal concentration]. The aqueous extract of Heracoleum Persicum failed to show antimicrobial activity, however, the methanol extract was effective against bacillus, streptococcous, enterococcous and nocardia. The methanol extract of Heracoleum Persicum has antibacterial activity. Further studies are strongly recommended to find out the possible therapeutic capability of this plant in infectious diseases