ABSTRACT
Delusional disorder is an uncommon mental illness with an estimated prevalence of 0.03%.Since these patients have no insight in their disease, psychotherapy of them accompanies by many problems. It seems that using an effective drug with least side effects has an important role in treatment of this disorder. The aim of this study is comparison of theraputic effects of Risperidone and Haloperidole in treatment and management of delusional disorders. In this study, 35 patients [22 male and 13 female] suffering from delusional disorders according to DSMIV criteria and diagnosis of a psychiatrist, were selected and randomly divided into two groups. The Global Assessment of Function-sale [GAF] was measured in patients before treatment and then one group received Risperidone [2-6 mg/day] and the other was treated with Haloperidole [10-20 mg/day] In the first group treated with Risperidone [19 cases] response to treatment was 89.5%, which was higher than the second group, which was treated with Haloperidole [16 cases] with 68.5% response to treatment [p=0.248]. The mean increase range of GAF in first group was higher than the second group [55 and 44 respectively] [p=0.003]. It seems that treatment of delusional disorder with Risperidone is more effective than Haloperidole and ends to more increase in GAF. In the meantime Resperidone is tolerated better and has fewer side effects
Subject(s)
Humans , Male , Female , Risperidone , HaloperidolABSTRACT
Research in medical science, as in all other fields of science, is necessary in order to maintain and improve the public health. This is achievable only by researchers and faculty members. This study is attempt to identify intra-organizational factors that influence research planning and related interventions in Tabriz Medical University. In this descriptive cross-sectional study, the study group included all faculty members and masters of science [equivalent to faculties] in Tabriz Medical University, of which 121 persons were selected randomly. Lickert style questionnaires were developed to evaluate and compare the attitudes toward project approval process, knowledge about research facilities, departmental cooperations in research, and researchers' capabilities in project execution. Data analysis was performed using SPSS software. During a 3 year period, each faculty member had, on average, supervised 5.17 dissertations, conducted 1.15 approved research projects, and had 3.4 presentations in domestic and 0.36 presentations in international conferences. Lack of time was the main problem in conducting research. Comparing faculties with and without research experience, there was significant differences in regard of access to research facilities [p<0.01], assessment of the benefits of research [p<0.02], and the level of research knowledge [p<0.02]; while no significant difference was found regarding motivations, job satisfaction, departmental cooperation, and expecting benefits from conducting research. According to the faculties' views, intra-organizational problems are less important than personal factors in performing research projects; i.e. the main obstacles for research were lack of time, and lack of competence in research methodology and problem-finding. Intra-organizational factors such as delay in project approval and lack of knowledge about research priorities are classified in the next levels