ABSTRACT
Fifty-three cases of carcinoma of prostate were registered in Civil Hospital, Karachi, Surgical Unit III and JPMC from 1st July, 1988 to 1st April, 1993. Nine patients were lost to follow-up, while 44 were included in this study. Carcinoma of prostate comprises 1.8% of all malignancies in male as reported in cancer registry of JPMC. Majority of the patients were between 61-70 years of age and almost half of them had one or more associated diseases, acute urinary retention was the commonest complaint at presentation followed by prostatism and haematuria. In seventy-five% of cases the disease was diagnosed in the stage where palliative rather than curative treatment could be undertaken. However, satisfactory palliation was obtained as the course of the disease is indolent. Those who received hormonal treatment more than thirty-one% developed complication attributable to treatment while the incidence of complications due to radiotherapy was about thirty-eight%. Chemotherapy was not found effective