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JPAD-Journal of Pakistan Association of Dermatologists. 2005; 15 (2): 113-118
in English | IMEMR | ID: emr-171409

ABSTRACT

Lippia nodiflora L, an indigenous herb has many medicinal uses. Present work was carried out to study the antifungal activity of crude extracts of L. nodiflora L. against the human pathogenic fungi. Crude extracts from the leaves and shoots of plant were prepared in different solvents including ethanol, methanol, ethyl acetate, chloroform and water and tested for antifungal activity against Aspergillus niger, A.. flavus, Paecilomyces varioti, Microsporum gypseum, and Trichophyton rubrum. Concentration of various elements e.g. Al, Ca, Cu, Fe, Mg, Mn, P, S and Zn were determined by using atomic absorption spectrophotometer and UV spectrophotometer. All crude extracts including ethanol, methanol, ethyl acetate, chloroform and aqueous extracts showed high activity against test organisms. Ethanol and aqueous extracts appeared to be the most effective antifungal agents as compared to methanol, chloroform and ethyl acetate. Moreover, the plant L. nodiflora L has high concentration of various essential elements. The medicinal plant Lippia nodiflora L contains considerable amount of elements which are important component of many formulation, used in skin care

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