ABSTRACT
Objective To evaluate the efficacy and safety of endovascular repair with covered stent in the treatment of Stanford B -type aortic dissection.Methods The clinical data of 40 patients with Stanford B -type aortic dissection who underwent endovascular repair with covered stent in the People 's Hospital of Suqian , Nanjing Drum-Tower Hospital Group from January 2012 to December 2017 were retrospectively analyzed .The incidence of complications before and after treatment , and its influence on the serum levels of IL -1β, INF -γ, VEGF were analyzed.After one year follow -up,the changes of quality of life score before and after surgery ,and the mortality, reoperation or interventional treatment within one year after operation were compared .Results Forty patients were successfully implanted with stent grafts ,5 cases of which had a small amount of endoleak ,1 case had postoperative cerebral infarction , and no complications such as paraplegia or renal failure were observed .Compared with before treatment,the serum levels of IL-1β,INF-γand VEGF were significantly down -regulated after treatment [(3.24 ± 0.19)ng/L vs.(2.02 ±1.16)ng/L,(2.65 ±0.23)ng/L vs.(1.14 ±1.27)ng/L,(1.51 ±0.17)ng/mL vs.(0.73 ± 0.34)ng/mL],the differences were statistically significant (t=5.037,P=0.001;t=6.071,P=0.000;t=7.314,P=0.000).After 1 year of follow-up,the mortality rate was 5.00％(2/40),and the rate of reoperation or intervention was 5.00％(2/40).The postoperative quality of life(QLQC-30) of the patients was scored in different dimensions:emotional function,body function,role function,cognitive function and social function after 1 month,6 months and 12 months,the differences were statistically significant (F=6.134,7.109,5.134,6.925,5.197,all P=0.000). Conclusion Endovascular repair with covered stent in the treatment of Stanford B aortic dissection can significantlyimprove the clinical symptoms of patients ,with significant effects and less complications ,and can significantly improve patients'survival and quality of life .
ABSTRACT
Objective@#To evaluate the efficacy and safety of endovascular repair with covered stent in the treatment of Stanford B-type aortic dissection.@*Methods@#The clinical data of 40 patients with Stanford B-type aortic dissection who underwent endovascular repair with covered stent in the People's Hospital of Suqian, Nanjing Drum-Tower Hospital Group from January 2012 to December 2017 were retrospectively analyzed.The incidence of complications before and after treatment, and its influence on the serum levels of IL-1β, INF-γ, VEGF were analyzed.After one year follow-up, the changes of quality of life score before and after surgery, and the mortality, reoperation or interventional treatment within one year after operation were compared.@*Results@#Forty patients were successfully implanted with stent grafts, 5 cases of which had a small amount of endoleak, 1 case had postoperative cerebral infarction, and no complications such as paraplegia or renal failure were observed.Compared with before treatment, the serum levels of IL-1β, INF-γ and VEGF were significantly down-regulated after treatment[(3.24±0.19)ng/L vs.(2.02±1.16)ng/L, (2.65±0.23)ng/L vs.(1.14±1.27)ng/L, (1.51±0.17)ng/mL vs.(0.73±0.34)ng/mL], the differences were statistically significant(t=5.037, P=0.001; t=6.071, P=0.000; t=7.314, P=0.000). After 1 year of follow-up, the mortality rate was 5.00%(2/40), and the rate of reoperation or intervention was 5.00%(2/40). The postoperative quality of life(QLQC-30) of the patients was scored in different dimensions: emotional function, body function, role function, cognitive function and social function after 1 month, 6 months and 12 months, the differences were statistically significant(F=6.134, 7.109, 5.134, 6.925, 5.197, all P=0.000).@*Conclusion@#Endovascular repair with covered stent in the treatment of Stanford B aortic dissection can significantly improve the clinical symptoms of patients, with significant effects and less complications, and can significantly improve patients' survival and quality of life.
ABSTRACT
Objective@#In order to master the epidemic trend of corona virus disease 2019 (COVID-19) and evaluate the effect of prevention and control, we evaluate the epidemic dynamics of COVID-19 in mainland China, Hubei province, Wuhan city and other provinces outside Hubei from January 16 to February 14, 2020.@*Methods@#We collected the daily number of new confirmed COVID-19 cases by nucleic acid detection reported by the National Health Commission from January 16, 2020 to February 14, 2020. The analysis includes the epidemic curve of the new confirmed cases, multiple of the new confirmed cases for period-over-period, multiple of the new confirmed cases for fixed-base, and the period-over-period growth rate of the new confirmed cases.@*Results@#From January 16 to February 14, 2020, the cumulative number of new confirmed cases of COVID-19 in mainland China was 50 031, including 37 930 in Hubei province, 22 883 in Wuhan city and 12 101 in other provinces outside Hubei. The peak of the number of new confirmed cases in other provinces outside Hubei was from January 31 to February 4, 2020, and the peak of new confirmed cases in Wuhan city and Hubei province was from February 5 to February 9, 2020. The number of new confirmed cases in other provinces outside Hubei showed a significant decline (23% compared with the peak) from February 5 to February 9, 2020, while the number of new confirmed cases in Wuhan city (30% compared with the peak) and Hubei Province (37% compared with the peak) decreased significantly from February 10 to February 14, 2020.@*Conclusion@#The epidemic prevention and control measures taken by the state and governments at all levels have shown very significant effects, effectively curbing the spread of the COVID-19 epidemic in China.