ABSTRACT
Objective To study the extraction technology of essential active components in compound shark cartilage capsules.Methods Astragalin and matrine,the essential active components in compound shark cartilage capsules,were taken as the test indexes.The extraction was optimized by using orthogonal design.Results The calibration curve for astragalin and matrine was linear over the range of 1～5?g and 2.2～11.0?g,respectively.The results suggested that the optimum conditions:Astragalus membranaceus Bge.∶water =1∶16,extracting for 2h,repeating 3 times for extraction of astragalin;Sophora flavescens Ait.∶water=1∶16,extracting for 2h for extraction of matrine.Conclusion The extraction technology was simple,reliable and could be used in guality control of extracting the essential active components in compound shark cartilage capsules.