ABSTRACT
Objective Applications and grants of young scientists fund on Health Sciences of National Natural Science Fund in Shanghai First People's Hospital,Shanghai Jiao Tong University during 2011-2015 were analyzed with an attempt to explore the ways to increase the funding rate.Methods x2 test and t test were performed,and a binary Logistic stepwise regression model was established to determine variables influencing the results of applications.Results During 2011-2015,504 applications were presented among which 119 were granted.The funding rate was higher than the average value of the Department of Health Sciences.The results of Logistic regression analysis indicated that degree and the highest impact factor of SCI articles published by applicants were the key determinants predicting whether an application will be granted or not.When applicants applied young scientists fund in one or two years after their postgraduate study,the funding rates were 35.51％ and 28.13％ respectively,which were both higher than the corresponding annual funding rates.It declined thereafter and became lower than the corresponding annual funding rates.Conclusions SCI article is an important aspect of academic achievements of applicants,which is a prerequisite for an application to be granted.However,a scientific and innovative project may be critical for the outcome of an application.The results of the current research suggest investigators apply young scientists fund as early as possible.
ABSTRACT
Objective Data on applications and grants of general program on health science of National Natural Science Fund from Shanghai First People's Hospital,Shanghai Jiao Tong University (SFPH) during 2011-2014 were analyzed with an attempt to explore the ways to promote the funding rate.Methods x2 test and t test were performed,and a binary Logistic regression model was established to determine variables influencing the results of applications.Results There were 367 applications in SFPH during 2011-2014,86 of which were granted.The funding rate was higher than that of Department of Health Science.The total and highest impact factor of SCI articles published by applicants of granted programs were both higher than those of non-granted programs.The significance of these two factors in predicting whether an application will be granted was confirmed by the results of Logistic regression analysis.Conclusions SCI article is an important aspect of academic achievements of applicants,which is a prerequisite for an application to be granted.However,a scientific and innovative project may be critical for the outcome of an application.
ABSTRACT
Objective To study the oxidative stress state of mice before and after air simulated diving. Methods Forty-eight mice were divided into 6 groups randomly. Every group was exposed to corresponding pressure for 60 minutes, twice a day for consecutive 3 days. Blood was obtained at the corresponding time to observe the changes of maleic dialdehyde, glutathione, glutathione-s-transferase, glutathione peroxidase, superoxide dismutase and catalase. Results Compared with the control, the activity of glutathione-s-transferase, glutathione peroxidase, superoxide dismutase, catalase and the level of glutathione were markedly inhibited and maleic dialdehyde increased in HO group and HA1 group (P