Effect of Azadirachta indica "Neem" Gum on blood glucose level in normal and diabetic rats

The tree Azadirachta indica A. Juss [N.O. Meliaceae], popularly known as Neem is an indigenous plant widely available in India. Almost every part of the tree has long been used in Unani system of medicine for the treatment of a variety of human ailments. The present study investigates the effect of oral administration of the Neem [Azadirachta indica] gum on blood glucose level in normal, glucose-fed hyperglycemic, adrenaline-induced hyperglycemic and alloxan-induced diabetic rats. Neem-gum [2 g/kg] was found to possess significant blood sugar lowering effect in adrenaline-induced hyperglycemic rats but such effect was not observed in normal, glucose-fed hyperglycemic and alloxan-induced diabetic rats