ABSTRACT
Background: Vascular disease Games the maximum mortality and morbidity burden in diabetic patents. Peripheral vascular disease is generally considered to be similar in its etiology and pathology to vascular disease in other tissue fields and its risk factors are also believed to be a part of larger atherogenic vascular picture
Methods: The study was conducted on a cohort of individuals suffering from Diabetes MelIitus registered at the [The Diabetes Management Center]. A total of 1160 cases were selected on the basis of presence or absence of peripheral artery disease with an aim to study the prevalence of peripheral vascular disease In diabetic and ascertain if total cholesterol, age and duration of diabetes play a role in the development of peripheral vascular disease
Results: Our study showed that presence of peripheral vascular disease in diabetics is significant; associated with increased age, increased duration of diabetes, history of intermittent claudication, delayed wound healing and Increased area of skin ulcers. There is no significant difference in total cholesterol level, LDL HDL, and triglyceride levels amongst those diabetics that developed PVD than those who did not The role of genetic susceptibilities leading to altered metabolism with due contribution by environmental factors may come to light by further analysis of other variables involved In artery disease picture
Conclusion: Presence of peripheral vascular disease in diabetics is significantly associated With Increased age Increased duration of dIabetes and history of intermittent claudication, delayed wound heating and increased area of skin ulcers. There is no significant difference in total cholesterol level LDL HDL and triglycerides levels amongst those diabetics that developed PVD than those who did not