ABSTRACT
Objective: Frequency of thyroid dysfunction in high risk pregnancies
Settings: Department of Obstetrics and Gynecology, Allied Hospital Faisalabad
Study design: Cross-sectional study
Duration of study: 16-06-2014 to 15-12-2014
Methodology: A total of 245 patients were included in this study. On the basis of TSH, T3, T4 reports thyroid dysfunction [hypothyroidism/hyperthyroidism] was observed
Results: Mean age of the patients was 29.43+/-5.21 years. Mean gestational age was 36.45 +/- 2.72 weeks. Thyroid dysfunction was observed in 63 patients [25.7%]. Out of theses 63 cases, Hypothyroidism fond in 44 [69.9%] and Hyperthyroidism in 19 patients [30.1%]. High risk pregnancy factors were IUGR in 85 patients [34.7%], GDM in 100 patients [40.8%], preeclampsia in 52 patients [21.2%] and IUFD in 8 cases [3.3%]. Distribution of high risk pregnancy factors in cases of thyroid dysfunction [n=63] were as follows: IUGR in 17 cases [27.0%], GDM, 20 cases [31.7%], preeclampsia in 18 cases [28.6%]. IUFD in 8 cases [12.7%]. Stratification of effect modifiers was carried out
Conclusion: The rate of thyroid dysfunction is increased in pregnant women with high-risk pregnancy. Under the currently recommended screening method, the majority of thyroid dysfunctions may be missing. With a full awareness of high incidence of thyroid dysfunction in pregnant women with obstetrical or medical complications, consideration should be given regarding the screening efficiency during pregnancy