ABSTRACT
This cross-sectional multicentric study was carried out by 7 Tunisian centers in the aim to describe their behavior about permanent insulin treatment, for there type 2 diabetic patients. Three hundred patients were included, aged 59.2 +/- 0.6 years, whose BMI was 2 7.3 +/- 0.28 kg/m2 and diabetic duration was 10.2 +/- 0.4 years at the time of insulin treatment. Most of them were previously treated by the association of glibenclamide and metformin with a fasting glycaemia at 16.7 +/- 0.3 mmol/l and HbAC at 11.1 +/- 0.2%. The insulin treatment was indicated in 68% of the cases by a chronic poor control, in 7.3% by an acute decompensation and in 20% by degenerative complications. Insulin regimen included 2 daily injections [60% of the cases]. Oral agents were stopped in 77% of the cases. After a mean delay of 3.6h0.2 years, the average insulin dose was 0.5610.02 UI/kg/j, the, fasting glycaemia was lowered by 7.0 +/- 0.4 mmol/l and the HbA1c by 2.2 +/- 0.2%. The investigators estimate that the insulin treatment was justified in 77% of the cases and was inevitable in 11%