ABSTRACT
The aim of the study is to explore the application of simultaneous treatment of spleen and kidney in the treatment of sarcopenia by sorting TCM literature and related research. It is believed that the location of sarcopenia is in the muscles and sinews, and the main pathological changes are located in the spleen and kidney, which is closely related to the kidney. The pathogenesis is deficiency of the spleen and kidney, muscle deprived of nourishment, and the treatment should focus on invigorating spleen and tonifying kidney. The mechanism of invigorating spleen and tonifying kidney in the treatment of sarcopenia may be related to improving mitochondrial function, reducing inflammatory factors, promoting insulin secretion and repairing muscle fibers.