ABSTRACT
Sickle cell anemia patients can develop various crises due to various triggers, infections being one of them. In our tertiary care centre, we have observed that post covid, there has been a rise in the number of infections leading to crisis in sickle cell patients, presenting experience of managing such cases. Aims and objectives were to study the pattern of infections in sickle cell crisis admitted from June 2020 to October 2022, compare the data to pre-cand to study etiology, complications and outcome in these patients. The increase found in the number of sickle cell crises post covid and the worsening outcome of these patients is suspected to be related to increased susceptibility to other infections of the community post changes made in the immune machinery of the human body by the CORONA Virus itself.