ABSTRACT
Background: Hyperhomocystenemia and genetic variants are factors for causing young age stroke glob-ally. This study aims to identify homocysteine related-MTHFR gene polymorphism that associated with recurrent cardiovascular outcomes. Methodology: A randomized controlled trial conducted upon 90 hyperhomocysteinemic ischemic stroke patients were taken from the neurology wards of a tertiary care hospital were randomly selected into vitamin B therapy group and control groups (n=45 in each group). Baseline subject details were col-lected venous blood sample for MTHFR genetic testing via PCR-RFLP technique along with blood homo-cysteine levels, vitamin B12, folic acid levels. Results: The results showed that the frequency of CT genotype polymorphism was 15.5% vs 13.3% for the MTHFR C677T gene without any significant difference between vitamin group and control group re-spectively (p-value >0.05). The reduction in mean homocysteine up to -6.77±4.50 versus -2.08±0.71 μmol/L in the vitamin group as compared to control group respectively, p value 0.001. Conclusion: Considerable amount of MTHFR gene polymorphism found among hyperhomocysteinemic ischemic stroke of sub-Himalayan region. Nutritional deficiencies including vitamin B 12 & folic acid, and some hidden reasons found, which could lead to the primary cause of hyperhomocysteinemia. Vitamin B therapy is an effective for reducing homocysteine.
ABSTRACT
Nearly one billion hectares of arid and semiarid areas of the world are salt affected and remain barren due to salinity or water scarcity. These lands can be utilized by adopting appropriate planting techniques and integrating trees with tolerant crops, forage grasses, oil yielding crops, aromatic and medicinal plants. Biosaline agroforestry provides various ecosystem services such as the improved soil fertility, carbon sequestration, and biomass production. Provisioning services relating to biomass production have been well studied in different biosaline agroforestry. Tree plantations and agroforestry enrich the soil in organic matter and exert a considerable ameliorative effect on soil properties. The soil microbial biomass serves as a useful indicator of soil improvement under salt stress. By integrating trees with the naturally occurring grassland systems on highly sodic soils, the soil organic carbon content increased from 5.3 Mg ha−1 (in sole grass) to 13.6, 10.9, and 14.2 Mg ha−1, when Dalbergia sissoo, Acacia nilotica, and Prosopis juliflora trees were introduced with grass. The strip-plantations of clonal Eucalyptus tereticornis sequestered 15.5 t ha–1 carbons during the first rotation of 5 years and 4 months. The soils of biosaline agroforestry could store 25.9–99.3 Mg C ha−1 in surface 0.3 m soil. Maintaining the stores and sink of carbon in agroforestry could play a key role in climate change mitigation as well as help in adaption changing environmental conditions.
ABSTRACT
Eight healthy female adult camels were used to study the effect of long term dehydration on serum constituents in extreme climatic conditions viz. cold and hot. The dehydration phases were of 24 days in cold and 13 days in hot conditions. The changes in sodium, potassium, calcium and phosphorus were non significant (P > 0.05) while in chloride, glucose, total proteins, urea, bilirubin, cholesterol and creatinine were significant (P < or = 0.05) during dehydration phase. The mean values of all the constituents tended to return to normal as the rehydration phase advanced. Changes in sodium and potassium in dehydrated camels reflected that they were able to maintain the salt balance.