Localization of glucose-6-phosphatase and fructose-1-6-diphosphaiase in subcellular fractions from different regions of the rat brain.

Two key enzymes of gluconeogenesis, glucose-6-phosphatase and fructosp-1-6- diphosphatase, were present in the cerebral hemispheres, the cerebellum and the brain stem of the rat brain. Significant activities of these-enzymes were associated with the particulate fraction.