ABSTRACT
Breast cancer is the most common cancer in females in the world. Breast aspiration cytology, histopathology and radiology have become important diagnostic tools in diagnosis of breast cancers. Objectives: Our aim was to conduct a combined diagnostic approach comprising of clinical examination, mammography, fine needle aspiration cytology and histopathology study in breast cancers correlate with individual diagnostic modality. Methods: A prospective study was done on 100 patients suspected of breast cancer. Various investigations including radiological investigations, FNAC, biopsy of the lesion was done. Clinical diagnosis, radiological, cytological and histopathology results were combined and compared with individual diagnostic modality. Results: Most common presenting symptom was breast lump seen in 95 cases. Out of 100 cases 47% were diagnosed malignant on radiology, 71% were malignant on Fine Needle Aspiration Cytology and 85% were diagnosed malignant on biopsy. On comparing all the three diagnostic procedures (radiology, FNAC and biopsy), the correlation came out to be highly significant. Conclusion: Though histopathological examination remains the gold standard for the diagnosis of these lesions, but an accurate clinical, radiological and cytological combined approach along with the histopathological examination aids in improving the diagnostic accuracy and reduce morbidity and mortality.
ABSTRACT
Background: The tubo-ovarian lesions manifest a wide spectrum of clinical, morphological, and histological features. Aims and objectives- To classify the lesions of tubes and ovaries and to correlate the various clinical and histopathological findings with age, chief complaints, and microscopic appearances of lesions. To correlate them radiologically and histopathologically. Methods: The present prospective study was based on the clinico-pathological correlation of various tubo-ovarian lesions in 75 cases over a period of 2 years. The histopathological reports were used to classify the tubo-ovarian lesions and correlate /substantiate the clinical and radiological findings. Results: Out of 75 cases, 51 (68%) ovarian, 18 (24%) tubal, and 6 (8%) cases showed simultaneous involvement of both tube and ovary. Amongst 18 tubal lesions,16 were of ectopic gestation (6 were ruptured) and the rest 2 of salpingitis. Amongst the ovarian lesions,41 cases were of ovarian neoplasms which were categorized as benign and malignant. Serous cystadenoma was the most common benign tumor and serous cystadenocarcinoma was the most malignant tumor. Conclusion: Clinical, radiological and histopathological diagnosis were compared and analysed statistically and the correlation was highly significant. An accurate clinical and radiological examination along with the histopathological examination aids in improving the diagnostic accuracy.